Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

Primary hepatocellular carcinoma is a devastating type of liver cancer. Silver nanoparticles (AgNPs) have been assessed for a variety of purposes, including being tested as an anticancer agent. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

Open Access Research Protective effect of COVID-19 vaccination against a SARS-CoV-2 reinfection in the Babil Province Fatima Adnan Alzubaidi1, Enass Najem Oubaid2, Zahraa I. J. Shubber3, Hussam Wahab Al-Humadi4, Rafal J. Al-Saigh5 1Department of Clinical Pharmacy, College of Pharmacy, University of Babylon, Hillah, Iraq 2Department of Pharmacognosy, College of Pharmacy, … Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

Vasculopathy is typically seen in diabetic patients, and can lead to foot ulcerations. Carbon dioxide (CO2) therapy was found to improve chronic wound healing in patients with vascular impairment. This type of therapy refers to the transcutaneous and subcutaneous application of CO2 as well as CO2 water baths for therapeutic purposes. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

Proteus mirabilis is a genus of bacteria that can cause foodborne diseases. We collected 100 canned food samples from local supermarkets in Hillah (Iraq), including juice (23%), milk products (22%), beef (20%), fish (14%), milk (12%), and tomato paste (9%) samples. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

The lack of safe and effective antiepileptic drugs is a persistent issue that could be addressed through the repurposing or further development of commonly available drugs. Due to high accuracy, low effort, and high cost, it is best to begin the search for alternative treatments with a theoretical chemical study. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

When nanotechnology is used in medicine, it makes it easier to find and treat a wide range of diseases. One of the oral options for treating multiple sclerosis (MS) is dimethyl fumarate (DMF). DMF has been shown to be effective in lowering inflammatory diseases; nevertheless, it is characterized by several undesirable side effects that reduce patient compliance and add financial obstacles. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

Globally, a massive amount of expired or leftover medications accumulates each year because of pharmaceutical overprescription, combined with overproduction. This pharmaceutical waste poses environmental, economic, and social/ethical challenges. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

Our study discusses the need for the development of alternative treatments for antiepileptic drugs. It proposes a theoretical chemical study using dioxoisoindoline derivatives and molecular docking in order to find potential alternative drugs. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

The current study shows the cytotoxicity effect of the Crassula ovata n-hexane extract on esophagus cancer. C. ovata is a perennial succulent plant belonging to the Crassulaceae family. In Africa, the leaves were used medicinally to cure epilepsy and diarrhoea by boiling them in milk. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

The aftermath of monsoon rains that fell in Pakistan from June to November 2022 were catastrophic as millions of people were affected, water systems were damaged, and agricultural production was affected. The floods aggravated the already existing nutrition crisis which largely increased children’s vulnerability. Continue reading