Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

Innovative methods and significant developments in designing new synthetic inorganic materials have been used to overcome limitations of current drug delivery systems. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

Network pharmacology as a “green approach”, predicting metabolite behaviours chemically and biologically and guiding biological experimental design, is a new strategy aiming to uncover the mechanism of action of natural products as drug candidates. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

Obesity is a worldwide issue that is progressively worsening. It can result in significant co-morbidities, including type 2 diabetes, cardiovascular disease, and obesity-related cancers. Current treatment options for obesity have several limitations, and the connection between obesity and cancer development is not well comprehended. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

  Open Access Keynote Speech The interaction of choline and one-carbon / folate metabolism derangements on the cardiac remodeling process with or without diabetes Charis Liapi1,2 1College of Pharmacy, University of Babylon, Hillah, Iraq 2Department of Pharmacology, Medical School, National and Kapodistrian University of Athens, Athens, Greece *Corresponding author: Charis … Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors, approved for the treatment of diabetes mellitus, have gained attention for their cardioprotective effect. The exact mechanism by which SGLT-2 inhibitors exert their cardioprotective effect remains unclear. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

Glucocorticoids are a class of steroid hormones, vital for mammalian life. They have a plethora of biological effects, mainly supporting metabolic, cognitive, and immunological functions. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

There is a growing body of literature highlighting the potential of game-based learning (GBL) in creating immersive, highly engaging, active learning experiences. Furthermore, advances in digital technology along with the demand for online learning during the COVID-19 pandemic has brought digital GBL to the forefront of innovative teaching practice. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

Due to their unique physical and chemical properties, the potential application of nanomaterials in medicine is particularly attractive. Despite the many advantages that nanomaterials can offer as diagnostic and therapeutic tools, their transition from the bench to clinical practice is extremely challenging. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

Smart nanopolymers with the capability to release drugs on demand and in response to specific illness signals, represent a promising avenue in the field of drug delivery. Their synthesis and characterization process involves the careful design of nanopolymeric structures, incorporating stimuli-responsive elements. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Supplementary Issue 2

Nanoinformatics is a next-generation method for designing and simulating nanodrug candidates. It involves combining bioinformatics and quantum tools to predict and evaluate drugs. This approach addresses scientific problems in cheminformatics, configuration optimization, drug development, and administration. The integration of bioinformatics and quantum tools is crucial for the understanding of these advancements. Continue reading