Τόμος 36 (2022) – Τεύχος 1 – Άρθρο 4 – Review of Clinical Pharmacology and Pharmacokinetics -Διεθνής Έκδοση – Volume 36 (2022) – Issue 1 – Article 4 – Review of Clinical Pharmacology and Pharmacokinetics – International Edition

Open Access-Title

Antioxidant Activity in Patients with Type II Diabetes

Author

Maria Trapali

Laboratory of Chemistry, Biochemistry, Cosmetic Science, Department of Medical Laboratories, University of West Attica, Aigaleo, Greece

Citation
M. Trapali. Antioxidant Activity in Patients with Type II Diabetes. Rev. Clin. Pharmacol. Pharmacokinet., Int. Ed.
36(1): 23-26 (2022). DOI: 10.5281/zenodo.8436470
Publication Date
Republication Date
03-05-2022
12-10-2023
Full Text Language

English

Keywords
Diabetes, antioxidant capacity, plasma, DPPH, free radicals
Other Terms

Research Article

Summary
Oxidative stress has been shown to be involved in many diseases including Diabetes. The aim of this study was the determination of antioxidant capacity in plasma of diabetic patients. The degree antioxidant capacity was calculated with DPPH assay, a method based on the scavenging of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical. Antioxidant activity was not statistically significantly lower than in control group (p<0.05).
References 1.Berlett, B. & Stadman, E., 1997. Protein oxidation in aging, disease, and oxidative stress. J Biol Chem, 272, 20313-316.
2. Janaszewska, A. & Bartosz, G., 2002. Assay of total antioxidant capacity, comparison of four methods as applied to human blood plasma. Scand J Clin Lab Invest, 62(3), 231-6.
3. Mancini, F. et al., 2018. Dietary antioxidant capacity and risk of type 2 diabetes in the large prospective E3N-EPIC cohort. Diabetologia, 61(2), 308-316.
4. Ousaaid, D. et al., 2020. Beneficial Effects of Apple Vinegar on Hyperglycemia and Hyperlipidemia in Hypercaloric-Fed Rats. J Diabetes Res, 9284987.
5. Papadopoulou, A., Karkalousos, P. & Trapali, M., 2022. Effects of Diabetes Mellitus upon Sperm Quality Insight into molecular level. Journal of Diabetes Mellitus, 12, 75-86.
6. Pisoschi, A., Cheregi, M. & Danet, A., 2009. Total antioxidant capacity of some commercial fruit juices: Electrochemical and spectrophotometrical approaches. Molecules, 14, 480-493.
7. Saeedi, P. et al., 2019. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas. Diabetes Research and Clinical Practice, 157, 107843.
8. Tabatabei, F. et al., 2021. Evaluation of the Relationship between Salivary Lipids, Proteins and Total Antioxidant Capacity with Gingival Health Status in Type-1 Diabetic Children. J Dent (Shiraz), 22(2), 82-89.
9. Trapali, M., 2021. Oxidic Degradation of Lipids in Patients with Type II Diabetes. Review of Clinical Pharmacology and Pharmacokinetics, 35(2), 75-78.
10. Van der Schaft, N. et al., 2019. Dietary antioxidant capacity and risk of type 2 diabetes mellitus, prediabetes and insulin resistance: the Rotterdam Study. Eur J Epidemiol., 34(9), 853-861.
11. Wild, S. et al., 2004. Aglobal prevalence of diabetes estimates for the year 2000 and projections for 2030. Diabetes Care, 27, 1047-1053.
12. Katoor, A. et al.,2017. Oxidative stress in Atherosclerosis. Curr Atheroscler Rep, 19(11), 42
13. Ginter E. et al., 2014. Antioxidants in health and disease. Bratisl Lek Listy, 115(10), 603-606.
Relative Papers
pISSN 1011-6583 • eISSN 2945-1922
Tagged , , , , , . Bookmark the permalink.

Comments are closed.