Τόμος 33 (2020) – Τεύχος 2 –Άρθρο 3 – Review of Clinical Pharmacology and Pharmacokinetics – Διεθνής Έκδοση – Volume 33 (2020) – Issue 2 – Article 3 – Review of Clinical Pharmacology and Pharmacokinetics – International Edition

Kalofiri Paraskevi¹, Kefala Vasiliki PhD²,  Biskanaki Foteini³

¹ Aesthetician Cosmetologist ΜSc.

²Professor, Aesthetician Cosmetologist, Pharmacist, Department of Biomedical Sciences. (Direction of Aesthetics and Cosmetology) School of Health Professions. University of West Attica .Campus 1, Athens .Greece

³ Aesthetician Cosmetologist ΜSc, Academic Scholar, Department of Biomedical Sciences. (Direction of Aesthetics and Cosmetology) School of Health Professions. University of West Attica. Campus 1, Athens .Greece

The increasing incidence of obesity is a serious public health challenge worldwide. People are gaining weight faster than they have in the past. Although the obesity epidemic is largely fueled by lack of exercise and poor nutrition, certain chemicals substances have been shown to potentially have a role in its etiology. (1) There is growing interest of scientific community in the possibility that endocrine disrupting chemicals (EDCs) may affect pathways related to obesity by altering cell signaling involved in weight and lipid homeostasis.  A substantial body of evidence suggests that a subclass of endocrine-disrupting chemicals (EDCs), which interfere with endocrine signaling, can disrupt hormonally regulated metabolic processes, especially if exposure occurs during early development. These chemicals might predispose some individuals to gain weight despite their efforts to limit caloric intake and increase levels of physical activity, so-called ‘obesogens’. However, over 80,000 documented synthetic chemicals, few of them have been tested to determine their effects on the endocrine system. (2)This review discusses the role of EDCs in the obesity epidemic. The research reviewed here provides knowledge that health scientists can use to update their research and decision-making processes.

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