Open Access Review Paper
Isotretinoin and psychiatric adverse effects: A literature review
Kleomenis Lotsaris1
, Vasiliki Sofia Grech2, Ioanna Grech3, Vasiliki Kefala3, Efstathios Rallis3
1Medical Doctor, Resident Psychiatrist in Psychiatry Department of General Hospital ofAthens “Evaggelismos”2Medical Doctor, Department of Care and Social Services, Healthcare Services, University of West Attica, Hellas
3Department of Biomedical Sciences. School of Health Professions. University of West Attica. Campus 1, Athens. Greece
Published: 17 February 2024; https://doi.org/10.61873/VUQT8301
Abstract
This literature review article discusses the use of isotretinoin and examines its association with psychiatric adverse effects, particularly depression and suicidal ideation. The article presents historical and molecular data on isotretinoin and delves into the literature regarding its psychiatric side effects in the treatment of acne vulgaris. It tries to answer in questions about whether the scientific community has overlooked the significance of the underlying disease and explores the awareness of healthcare professionals regarding these potential adverse effects. Additionally, it investigates the likelihood of these effects based on the available literature to date.
Keywords: isotretinoin, suicide, depression, psychiatry, adverse effects
Please cite as:
Lotsaris K., Grech V.S., Grech I., Kefala K., Rallis E. Isotretinoin and psychiatric adverse effects: A literature review. Rev. Clin. Pharmacol. Pharmacokinet., Int. Ed. 38(Sup1):23-29 (2024).
https://doi.org/10.61873/VUQT8301