Title | Formation of acetamido-homo-aza-steroids and bis homo-aza-steroids by Beckmann rearrangement | |
Author | Panayotis Catsoulacos
Laboratory of Pharmaceutical Chemistry, University of Patras, Greece |
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Citation | Catsoulacos, P. : Formation of acetamido-homo-aza-steroids and bis homo-aza-steroids by Beckmann rearrangement, Epitheorese Klin. Farmakol. Farmakokinet. 2(2): 91-102 (1988) | |
Publication Date | 1988-10 | |
Full Text Language | English | |
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Keywords | Beckmann, rearrangement, steroidal oximes, formation, bis homo-aza-steroids, acetamido-homo-aza-steroids, carboxylic, leukemia, solid tumors. | |
Other Terms | review article | |
Summary | In this review article the Beckmann rearrangement of steroidal oximes and the formation of bis homo-aza-steroids and acetamido-homo-aza-steroids are reported. It is concluded that steroidal lactam is required for activity of homo-aza-steroidal esters of carboxylic derivatives of N,N-bis (2-chloroethyl) aniline in leukemias and solid tumors. | |
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Relative Papers | Structure-antileukemic activity relationships of modified steroidal alkylating agents in P388 and L1210 murine leukemias
Panayotis Catsoulacos |
Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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