| Title | Action de certains medicaments antiarythmiques sur l’ absorption de digoxine in vitro | |
| Authors | B. Kokkas, M. Kotoula, A. Kouyoumtzis, K.L. Papadopoulos et A. Paradelis
Laboratoire de Pharmacologie Expirimentale, Ecole de Medecine, University de Thessalonique, Grece |
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| Citation | Kokkas, B., Kotoula, M., Kouyoumtzis, A. Papadopoulos, K.L., Paradelis, A.: Steroidal alkylating agents in cancer chemotherapy, Epitheorese Klin. Farmakol. Farmakokinet. 3(1): 60-62 (1989) | |
| Publication Date | 1989-07 | |
| Full Text Language | French | |
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| Keywords | Action, medicaments antiarythmiques, amiodarone, mexiletine, propafenone, absorption, digoxine, tissue, hepatique. | |
| Other Terms | review article | |
| Summary | L ‘action des medicaments antiarythmiques amiodarone, mexiletine et propafenone sur l’ absorption de la digoxine par certains tissus de lapin a ete etudiee in vitro en utilisant de fa digoxine marquee par l’ iode 125. On a trouve que la propafenone reduit de 22,8% l’ absorption de fa digoxine par le tissu cardiaque. L’ amiodarone et fa mexifetine exercent le meme effet sur le tissu hepatique en reduisant l’absorption de la digoxine de 16,5% et 12,9% respectivement (p<0,05). | |
| References | 1. Aladjem, M., Kaplinsky, C., Wolfish, N„ Laufer, Y., Halkin, H.: Maturation of renal tubular transport of digoxin. Pediatr. Res. 19: 282 (1918)
2. Aronson, J.: Cardiac glycosides and drugs used in dysrhythmias. In: Meyler’s Side Effects of Drugs. (Dukes, ed.). Elsevier Scientific Publishing Co., Amsterdam, 1984. 3. J. Green, D. Margerison (eds): Statistical treatment of experimental data. Elsevier Scientific Publishing Co., Amsterdam, 1978. 4. P. Hasten (ed.): Drug interactions. Lea and Febiger, Philadelphia, 1985. 5. Paradelis, A., Zaimis, E.: Organ culture medium in substitution for physiological salines. J. Physiol. 201: 104 (1969) 6. A. Paradelis (ed.): Drug interactions. University Studio Press, Thessaloniki, 1985. |
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| Relative Papers |
Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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| ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 1989 – ANNUAL SUBSCRIPTION 1989 | |
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