Title | The role of mucosal immunity in respiratory tract infections: a new therapeutic concept | |
Author | Alfred de Courten
Geneva, Switzerland |
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Citation | de Courten, A.: The role of mucosal immunity in respiratory tract infections: a new therapeutic concept, Epitheorese Klin. Farmakol. Farmakokinet. 4(2): 105-111 (1990) | |
Publication Date | Received for publication: March 30, 1990
Accepted for publication: April 20, 1990 |
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Full Text Language | English | |
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Keywords | Mucosal immunity system, respiratory tract infections, macrophages, T- and B-lymphocytes, immunobiotherapy, Broncho-Vaxom. | |
Other Terms | review article | |
Summary | The complex mucosal immune system with its immunocompetent cells (macrophages, T and B lymphocytes) plays a key role in the induction of immune responses. The functional co-operation between the intestinal immune system known as the gut-associated lymphoid tissue (GALT) and that of the lung called the bronchus-associated lymphoid tissue (BALT) has made possible a new therapeutic concept for oral immunization, through the GALT, to overcome infections in the respiratory tract. Based on this new concept Broncho-Vaxom, an orally administered a cellular immunotherapy containing bacterial fractions, has been developed. Broncho-Vaxom was found to improve the impaired immunity of the respiratory passages through restoration of the immune functions of the macrophages, the T and B lymphocytes. This was always accompanied by improvement of the clinical findings and an excellent tolerance. | |
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