| Title | Geometric isomerism of tricyclic systems with central ring containing one or two heteroatoms: differences of the isomers in the intensity of pharmacological activity | |
| Authors | Panayotis Catsoulacos and Dimitris Catsoulacos
Laboratory of Pharmaceutical Chemistry, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece |
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| Citation | Catsoulacos, P., Catsoulacos, D.: Geometric isomerism of tricyclic systems with central ring containing one or two heteroatoms: differences of the isomers in the intensity of pharmacological activity, Epitheorese Klin. Farmakol. Farmakokinet. 5(2): 103-106 (1991) | |
| Publication Date | Received for publication: 15 August 1991
Accepted for publication: 20 August 1991 |
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| Full Text Language | English | |
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| Keywords | Thioxanthen-Δ9-alkylamines, Xanthen-A9-alklylamines, phenothiazine derivatives, geometric isomerism, pharmacological activity. | |
| Other Terms | review article | |
| Summary | Tricyclic systems with central ring containing one or two heteroatoms are discussed. For maximal pharmacological activity in the geometric isomers of thioxanthene, it is important the double bond between carbon nine and side chain, substitution at carbon two in the nucleus and cis configuration at the double bond. | |
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Online ISSN 1011-6575
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