| Title | Intravenous urine alkalinization in high dose methotrexate (HDMTX) treatment: a short communication | |
| Authors | N. Tsavaris¹, A. Karabelis¹, P. Vonorta*, N. Karvounis¹, D. Papagrigoriou², E. Tsoutsos¹, D. Halividi-Kozatsani¹, P. Koutsiouba-Kazakou² and P. Kosmidis¹
1. Second Department of Medical Oncology “Metaxa” Cancer Hospital, Piraeus, 185 37, Greece 2. Department of Nuclear Medicine “Metaxa” Cancer Hospital |
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| Citation | Tsavaris, N., Karabelis, A., Vonorta, P., Karvounis, N., Papagrigoriou, D. et al.: Intravenous urine alkalinization in high dose methotrexate (hdmtx) treatment: a short communication, Epitheorese Klin. Farmakol. Farmakokinet. 5(2): 107-109 (1991) | |
| Publication Date | Received for publication: 25 June 1991
Accepted for publication: 15 September 1991 |
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| Full Text Language | English | |
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| Keywords | High dose of methotrexate, intravenous urine alkalinization. | |
| Other Terms | review article | |
| Summary | The combined intravenous administration of bicarbonate, along with the intake of potassium chloride, mannitol and follinic acid, are well accepted measures by patients under high doses of methotrexate treatment. | |
| References | 1. Jolivet, J., Cowan, K.H., Curt, G.A., Chendenin, N.J., Chabner, B.A.: The pharmacology and the clinical use of methotrexate. The New Engl. J. Med. 309: 1094 (1983)
2. Jeffrey, J.E., Eilbert, F.R., Grant, T.T., Mirra, J.M., Weisenberg, T.H., Dorey, F.J.: Management of stage IIB Osteogenic Sarcoma: Experience at the University of California Los Angeles. Cancer Treat. Symp. 3: 117 (1985) 3. Jaffe, N., Frei, E., Watts, H., Tranggis, D.: High dose methotrexate in osteogenic sarcoma: A 5-year experience. Cancer Treat. Rep. 62: 259 (1978) 4. Tsavaris, N., Tsigalakis, D., Lafi, A., Vonorta, K., Papaioannou, Karvounis, N., Karagiaouris, P., Karabelis, A., Kosmidis, P.: High dose methotrexate: Pharmacology and clinical use. Rev. Clin. Pharmacol. Pharmacokinet. 4: 43 (1986) |
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| Relative Papers |
Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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