Title | Marihuana use during pregnancy | |
Authors | Anna Deltsidou
Technological Educational Institution of Lamia, Lamia, Greece |
|
Citation | Deltsidou, A.: Marihuana use during pregnancy, Epitheorese Klin. Farmakol. Farmakokinet. 17(3): 153-158 (2003) | |
Publication Date | Received for publication: 10 July 2003
Accepted for publication: 25 September 2003 |
|
Full Text Language | English | |
Order – Buy | Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €)
pharmakonpress[at]pharmakonpress[.]gr |
|
Keywords | Marihuana abuse and pregnancy, birth defects, congenital anomalies, prenatal cannabis exposure, substance abuse and pregnancy. | |
Other Terms | review article | |
Summary | Subject of this literature review, is the impact of marihuana/cannabis abuse during pregnancy and their long-term consequences on the fetus. Prenatal marihuana use was significantly related to increased hyperactivity, impulsivity, and inattention symptoms and in a small sample of women who used marihuana during pregnancy, investigators found an increased incidence of meconium-stained fluid, abnormal labors and placental abruption. A larger epidemiologic study reported lower birth weights, increased preterm deliveries and more major malformations in infants of marihuana users. The studies of the effect of prenatal marihuana exposure on the newborn have produced conflicting results and marihuana has not been definitively implicated as a teratogenic agent in humans. | |
References | 1. Kefala V., Protopapa E.E., Plessas S.T.: An esthetic problem. Prevention or treatment? Epitheor. Klin. Farmakol. Farmakokinet Intern. Ed. 15: 33-42 (2001)
2. Deltsidou A., Lykeridou K., Plessas S.: Licit substance abuse during pregnancy and its effects on the fetus. Epitheor. Klin. Farmakol. Farmakokinet. Intern. Ed. 15: 21-32 (2001) 3. National Institute of Drug and Alcohol Abuse: National pregnancy and health survey-drug use among women delivering live births. MD NCADI Publication no. BKD192 (1992) 4. Κοκκέβη A., Στεφανής K.: Τα ναρκωτικά στην Ελλάδα: Η διαχρονική πορεία της χρήσης. Ερευνητικό Πανεπιστημιακό Ινστιτούτο Ψυχικής Υγιεινής, Αθήνα: 71-78, 191-197 (1994) 5. Lee E.W., D’ Alonzo G.E.: Cigarette smoking, nicotine addiction and pharmacologic treatment. Arch. Intern. Med. 153: 34-48 (1993) 6. Youngstrom N.: Fetal alcohol syndrome carries severe deficits. APA Monitor 23(4): 32 (1992) 7. Hollister L., Reaven G.: Delta-9-tetrahydrokannabinol and glucose tolerance. Clin. Pharmacol. Ther. 16: 297- 302 (1974) 8. Malanga C.J., Kosofsky B.E.: Mechanisms of action of drugs of abuse on the developing fetal brain. Clin. Perinatol. 26(1): 17-37, v-vi (1999) 9. Lee M.J.: Marihuana and Tobacco use in pregnancy. Obstet. Gynecol. Clin. North Am. 25: 65-78 (1998) 10. Klausner R, Dingell J.: The metabolism and excretion of Δ9-tetrahydrocannabinol in the rat. Life Sci. 10: 49-59 (1971) 11. Kreutz D., Axelrod J.: Delta-9-tetrahydrocannabinol: Localization in body fat. Science 179: 391-392 (1973) 12. Heikkila J.I., Fritchie G.C., Engleber L.T., Ho B.T., Mclsaac W.M.: Placental transfer of tritiated 1-D9-tetrahydrocannabinnol. N. Engl. J. Med. 281: 330 (1969) 13. Jones R.: Human effects: An overview. NIDA Res. Monogr. 31: 54-80 (1980) 14. Elsohly M.A., Stanford D.F., Murphy T.P., et al.: Immunoassay and GC-MS procedures for the analysis of drugs of abuse in meconium. J. Anal. Toxicol. 23: 436-45 (1999) 15. Day N.L., Ritsardson G.: Prenatal marihuana use: Epidemiology, methodologic issues, and infant outcome. Clin. Perinatol. 18: 77-91 (1991) 16. Kline J., Stein Z., Hutzler M.: Cigarettes, alcohol and marihuana: Varying associations with birthweight. Intern. J. Epidemiol. 16: 44-51 (1987) 17. Bennett A.D.: Perinatal substance abuse and the drug-exposed neonate. Adv. Nurse Pract. 7(5): 32-6; quiz 37-8 (1999) 18. Shiono P.H., Klebanoff M.A., Nugent R.P., et al.: The impact of cocaine and marihuana use on low birth weight and preterm birth: a multicenter study. Am. J. Obstet. Gynecol. 172 (1 Pt 1): 19-27 (1995) 19. Balle J., Olofsson M.J., Hilden J.: [Cannabis and pregnancy]. Ugeskr. Laeger. 161: 5024-5028 (1999) 20. Hingson R., Alpert J.J., Day N., et al.: Effects of maternal drinking and marihuana use on fetal growth and development. Pediatrics 70: 539-546 (1982) 21. Witter F.R., Niebyl J.R.: Marihuana in pregnancy and pregnancy outcome. Am. J. Perinatol. 7: 36-38 (1990) 22. Greenland S., Richwald G.A., Honda G.D.: The effects of marihuana use during pregnancy. II. A study in a low-risk home-delivery population. Drug Alcohol Depend. 11: 359-366 (1983) 23. Linn S., Schoenbaum S.C., Monson R.R., et al.: The association marihuana use with outcome of pregnancy. Am. J. Public Health 73: 1161-1164 (1983) 24. Conner C.S.: Marihuana and alcohol use in pregnancy. Drug Intell. Clin. Pharm. 18: 233-234 (1984) 25. Behnke M., Eyler F.D.: The consequences of prenatal substance use for the developing fetus, newborn, and young child. Int. J. Addict. 28: 1341-1391 (1993) 26. Zuckerman B., Frank D., Hingson R., et al.: Effects of maternal marihuana and cocaine use on fetal growth. N. Engl. J. Med. 320: 762-768 (1989) 27. Braunstein G.D., Buster J.E., Soares J.R., et al.: Pregnancy hormone concentrations in marihuana users. Life Sci. 33: 195-199 (1983) 28. Fried P.A., Watkinson B., Gray R.: Growth from birth to early adolescence in offspring prenatally exposed to cigarettes and marihuana. Neurotoxicol. Teratol. 21: 513-525 (1999) 29. Day N., Cornelius M., Goldschmidt L., Richardson G., Robles N., Taylor P.: The effects of prenatal tobacco and marihuana use on offspring growth from birth through 3 years of age. Neurotoxicol. Teratol. 14: 407-414 (1992) 30. Fried P.A., Watkinson B.: 12- and 24-month neurobehavioural follow-up of children prenatally exposed to marihuana, cigarettes and alcohol. Neurotoxicol. Teratol. 10: 305-313 (1988) 31. Walker A., Rosenberg M., Balaban-Gil K.: Neurodevelopmental and neurobehavioral sequelae of selected substances of abuse and psychiatric medications in utero. Child Adolesc. Psychiatr. Clin. N. Am. 8: 845-867 (1999) 32. Fried P.A., Watkinson B., Dillon R.F., Dulberg C.S.: Neonatal neurological status in a low-risk population after prenatal exposure to cigarettes, marihuana, and alcohol. J. Dev. Behav. Pediatr. 8: 318-326 (1987) 33. Fried P.A., O’Connell C.M., Watkinson B.: 60- and 72- month follow-up of children prenatally exposed to marihuana, cigarettes, and alcohol: cognitive and language assessment, J. Dev. Behav. Pediatr. 13: 383-391 (1992) 34. Cornelius M.D., Taylor P.M., Geva D., Day N.L.: Prenatal tobacco and marihuana use among adolescents: effects on offspring gestational age, growth, and morphology. Pediatrics 95: 738-743 (1995) 35. Qazi Q.H., Mariano E., Milman D.H., et al.: Abnormalities in offspring associated with prenatal marihuana exposure. Dev. Pharmacol. Ther. 8: 141-148 (1985) 36. Hatch E., Bracken M.: Effects of marijuana use in pregnancy on fetal growth. Am. J. Epidemiol. 124: 986-993 (1986) 37. Scher M.S., Richardson G.A., Coble P.A., et al.: The effects of prenatal alcohol and marihuana exposure: disturbances in neonatal sleep cycling and arousal. Pediatr. Res. 24: 101-105 (1988) 38. Sherwood R.A., Keating J., Kavvadia V., et al.: Substance misuse in early pregnancy and relationship to fetal outcome. Eur. J. Pediatr. 158: 488-492 (1999) 39. Day N.L., Richardson G.A., Goldschmidt L, et al.: Effect of prenatal marihuana exposure on the cognitive development of offspring at age three. Neurotoxicol. Teratol. 16: 169-175 (1994) 40. Fried P.A.: Prenatal exposure to marihuana and tobacco during infancy, early and middle childhood: effects and an attempt at synthesis. Arch. Toxicol. Suppl. 17: 233- 260(1995) 41. Grufferman S., Schwartz A.G., Ruymann F.B., Maurer H.M.: Parents’ use of cocaine and marihuana and increased risk of rhabdomyosarcoma in their children. Cancer Causes Control 4: 217-224 (1993) 42. Goldschmidt L., Day N.L., Richardson G.A.: Effects of prenatal marihuana exposure on child behavior problems at age 10. Neurotoxicol. Teratol. 22: 325-336 (2000) 43. Fried P.A., Watkinson B.: Visuoperceptual functioning differs in 9- to 12-year olds prenatally exposed to cigarettes and marihuana. Neurotoxicol. Teratol. 22: 11-20 (2000) 44. Eyler F.D., Behnke M.: Early development of infants exposed to drugs prenatally. Clin. Perinatol. 26: 107-150, vii (1999) 45. Cayol V., Corcos M., Clervoy P., Speranza M.: [Pregnancy and drug abuse: current situation and therapeutic strategies], Ann. Med. Interne. (Paris) 151 Suppl B: 20-6 (2000) 46. Blondel S., Lefebvre P., Tondeur M., Blum D.: [Neonatal abstinence syndrome: current and future aspects]. Rev. Med. Brux. 14(3): 73-77 (1993) 47. Kelly J.J., Davis P.G., Henschke P.N.: The drug epidemic: effects on newborn infants and health resource consumption at a tertiary perinatal centre. J. Paediatr. Child Health 36: 262-264 (2000) 48. Sarman I.: Methadone treatment during pregnancy and its effect on the child. Better than continuing drug abuse, should be monitored by a specialized antenatal care center]. Lakartidningen 97: 2182-2184, 2187-2188, 2190 (2000) 49. Agarwal P., Rajadural V.S., Bhavani S., Tan K.W.: Perinatal drug abuse in KK Women’s and Children’s Hospital. Ann. Acad. Med. Singapore 28: 795-799 (1999) 50. Schneider C., Fischer G., Diamant K., et al.: [Pregnancy and drug dependence], Wien. Klin. Wochenschr. 108: 611-614 (1996) 51. Habbick B.: Fetal alcohol syndrome in Saskatchewan: unchanged incidence in a 20-year period. Can. J. Public Health 87: 204-207 (1996) 52. Deltsidou A.: Opioids and Methadone Exposure during Pregnancy. Epitheor. Klin. Farmakoi. Farmakokinet. Intern. Ed. 16: 207-212 (2002) 53. Deltsidou A.: Cocaine Abuse in Pregnancy. Epitheor. Klin. Farmakoi. Farmakokinet. Intern. Ed. 3S: 225-232 (2001) 54. Lindenskov L., Johnsen K., Larsen K., Lange A.P.: Pregnancy and drug abuse. Ugeskr. Laeger. 161: 5005- 5009 (1999) |
|
Relative Papers |
Online ISSN 1011-6575
Άρθρα Δημοσιευμένα σε αυτό το Περιοδικό Καταχωρούνται στα:
- Chemical Abstracts
- Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
Συντακτικη Επιτροπή-Editorial Board
ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 2003– ANNUAL SUBSCRIPTION 2003 | |
Γλώσσα Πλήρους Κειμένου – Full Text Language | Αγγλικά – English |
Παραγγελία – Αγορά – Order – Buy | Ηλεκτρονική Μορφή: pdf (70 €) – Digital Type: pdf (70 €)
pharmakonpress[at]pharmakonpress[.]gr |
Έντυπη Μορφή (70 € + έξοδα αποστολής) – Printed Type (70 € + shipping)
pharmakonpress[at]pharmakonpress[.]gr |