Τόμος 7 (1993) – Τεύχος 2 – Άρθρο 2 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 7 (1993) – Issue 2 – Article 2 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

 

Title Continuous spinal anesthesia with combination of local anesthetics: Combination of hyperbaric lidocaine with two different concentrations of bupivacaine for spinal anesthesia
Authors P.G. Maidatsi¹, K.B. Kapinas², N.K. Gorgias³ and M.N. Tsolaki²

1.   Department of Anesthesiology, Saint Demetrios General Hospital, E. Zographou 2, 54634 Thessaloniki, Greece

2.   3rd Neurologic Clinic of Aristotelian University of Thessaloniki, G. Papanikolaou General Hospital, Exohi 52010, Thessaloniki, Greece

3.   Department of Anesthesiology, Kilkis General Hospital, 61100 Kilkis, Greece

Citation Maidatsi, P.G., Kapinas, K.B., Gorgias, N.K., Tsolaki, M.N.: Continuous spinal anesthesia with combination of local anesthetics: Combination of hyperbaric lidocaine with two different concentrations of bupivacaine for spinal anesthesia, Epitheorese Klin. Farmakol. Farmakokinet. 7(2): 74- 78 (1993)
Publication Date Received for publication. 15 May 1993

 Accepted for publication. 15 June 1993

Full Text Language English
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Keywords Anesthesia, aged patients, anesthetics local, bupivacaine, lidocaine anesthetics techniques, continuous spinal anesthesia.
Other Terms review article
Summary Hyperbaric lidocaine with 0.5% bupivacaine is often used spinally, providing anesthesia with rapid onset and satisfactory duration, although complicated with arteria hypotension, especially undesirable in aged patients. This study was designed to determine, whether combinations of lidocaine with lower than 0.5% concentrations of bupivacaine provides sufficient analgesia, without severe hypotension. We studied 31 patients undergoing elective surgery with a continuous spinal technique. Group A received 1 ml of 5% lidocaine and 2 ml of 0.5% bupivacaine, while group B received the same dose of lidocaine and 2 ml of 0.125 bupivacaine. During observation we assessed level of sensory block, motor block and the need of additional spinal administration of the previous used solution in both groups. We also studied arterial pressure and heart rate during the procedure. Spinal combination of 5% lidocaine with high and low concentration of bupivacaine provides sufficient analgesia in aged patients but the consequent hemodynamic changes are insignificant only when low concentration of bupivacaine is used.
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