| Title | Non-invasive assessment of silent ischaemia using nuclear medicine techniques | |
| Author | Constantine L. Papadopoulos and Argyrios S. Doumas
2nd Department of Cardiology, Aristotelian University of Thessaloniki, Greece |
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| Citation | Papadopoulos, C.L., Doumas, A.S.: Non-invasive assessment of silent ischaemia using nuclear medicine techniques, Epitheorese Klin. Farmakol. Farmakokinet. 7(3): 113-115 (1993) | |
| Publication Date | Received for publication: 1 December 1993
Accepted for publication: 10 December 1993 |
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| Full Text Language | English | |
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| Keywords | Silent ischaemia, non-invasive assessment, nuclear medicine techniques. | |
| Other Terms | review article | |
| Summary | The development of the portable scintillation probe for the evaluation of the left ventricular (LV) function during routine activities is valuable in the investigation of silent ischaemia. However, it has been shown that assessment of ambulatory ischaemia is of additional clinical value in patients with chronic coronary artery disease (CAD), beyond that provided by exercise-induced ischaemia. Exercise Thallium-201 (Tl-201) scintigraphy and radionuclide angiography play a prominent role in the management of patients with asymptomatic or mildly sympomatic CAD. Screening strategies are reasonable to apply only to population with a high likelihood of disease. | |
| References | Silent Ischaemia during ambulatory activities
1. Deanfield, J.E., Maseri, A., Selwyn, A.P., et al.: Myocardial ischaemia during daily life in patients with stable angina: its relation to symptoms and heart rate changes. Lancet 2: 753-758 (1983) 2. Selwyn, A.P., Allan, R.M., L’ Abbate A.L. et al.: Relation between regional myocardial uptake of rubidium-82 and perfusion: absolute reduction of cation uptake in ischaemia. Am. J. Cardiol. 50: 112-119 (1982) 3. Selwyn, A.P., Shea, M., Deanfield, J., et al.: The character of transient myocardial ischaemia: clinical studies and progress using positron emission tomography. Int. J. Card. Imag. 1: 61-72 (1985) 4. Quyyumi, A.A., Crake, T., Wright, C., et al.: The role of ambulatory ST-segment monitoring in the diagnosis of coronary artery disease: comparison with exercise testing and thallium scintigraphy. Eur. Heart J. 8: 124-129 (1987) 5. Tamaki, N., Yasuda, T., Moore, R., et al.: Continuous monitoring of left ventricular function by an ambulatory radionuclide detector in patients with coronary artery disease. J. Am. Coll. Cardiol. 12: 669-679 (1988) Exercise-induced silent ischaemia 1. Falcone, C., De Servi, S., Poma, E., et al.: Clinical significance of exercise-induced silent myocardial ischaemia in patients with coronary artery disease, J. Am. Coll. Cardiol. 9: 295-299 (1987) 2. Assey, M.F., Walters, G.L., Hendrix, G.H., et al.: Incidence if acute myocardial infarction in patients with exercise-induce silent myocardial ischaemia. Am. J. Cardiol. 59: 725-729 (1987) 4. Bonow, R.O., Bacharach, S.L., Green, M.V., et al.: Prognostic significance of symptomatic versus asymptomatic (silent) myocardial ischaemia induced by exercise in mildly symptomatic and in asymptomatic patients with angiographically documented coronary artery disease. Am. J. Cardiol. 60: 778- 783 (1987) Screening asymptomatic population for silent ischaemia 1. Berman, D.S., Rozanski, A., Knoebel. S.B.: The detection of silent ischaemia: cautions and precautions. Circulation 75: 101-105 (1987) 2. Rozanski, A., Berman, D.S.: Silent myocardial ischaemia. I. Pathophysiology, frequency of occurrence, and approaches toward detection. Am. Heart J. 114: 615-626 (1987) 3. Rozanski, A., Berman, D.S..: Silent myocardial ischaemia. II. Prognosis and implications for the clinical assessment of patients with coronary artery disease. Am Heart J. 114: 627-638 (1987) 4. Epstein, S.E., Quyyumi, A.A., Bonow, R.O.: Myocardial ischaemia: silent or symptomatic. N. Engl. J. Med. 318: 1038-1043 (1988) 5. Epstein, S.E., Quyyumi, A.A., Bonow, R.O.: Sudden cardiac death without warning: possible mechanisms and implications for screening asymptomatic populations. N. Engl J. Med. 321: 320-324 (1989) |
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| Relative Papers |
Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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| ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 1993 – ANNUAL SUBSCRIPTION 1993 | |
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