| Title | Hemodynamic effects of octreotide in critically ill intensive care unit (ICU) patients | |
| Authors | G. Baltopoulos², G. Kofinas¹, G. Panetsos¹, G. Fildisis², S. Karatzas² and A. Kakouri¹
1. Department of Internal Medicine, Division of Critical Care, Ippocration General Hospital, Athens, Greece 2. Department of Surgery, Division of Critical Care, Agioi Anargyroi Cancer Hospital, Kifissia, Athens, Greece. |
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| Citation | Baltopoulos, G., Kofinas, G., Panetsos, G, Fildisis, G., Karatzas, S. et al: Hemodynamic effects of octreotide in critically ill intensive care unit (ICU) patients, Epitheorese Klin. Farmakol. Farmakokinet. 7(3): 123-126 (1993) | |
| Publication Date | Received for publication: 15 October 1993
Accepted for publication: 15 November 1993 |
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| Full Text Language | English | |
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| Keywords | Octreotide, somatostatin, hemodynamic effects, critically ill. | |
| Other Terms | review article | |
| Summary | Octreotide (Sandostatin) is a selective vasoconstrictor of the splachnic vasculature, without any significant effect on the systemic circulation when it is administered in an intravenous (i.v.) infusion. In order to clarify the acute hemodynamic effects of bolus i.v. octreotide administrations, we studied 15 critically ill ICU patients, prior catheterized with a Swan-Ganz catheter and scheduled to receive bolus i.v. octreotide, for reasons independent of the study. The results showed a transient (5 minute maximum duration), but statistically significant change in hemodynamic profile of pulmonary circulation as well as in the hepatic vein diameter. Also, transient, but not statistically significant changes, were recorded in the systemic hemodynamic profile | |
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Online ISSN 1011-6575
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