Τόμος 11 (1997) – Τεύχος 2 & 3 – Άρθρο 14 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 11 (1997) – Issue 2 & 3 – Article 14 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Combinatorial synthesis in medicinal chemistry: implications in drug discovery and development
Authors Julian Smith1 and Tony Cooper2

1. Department of Chemistry, University of Exeter, Stocker Road, Exeter, Devon, U.K., EX4 4QD

2. Receptor Research Limited, Wainhouse Comer, Bude, Cornwall; U.K. EX23 OAR

Citation Smith, J., Cooper, T.: Combinatorial synthesis in medicinal chemistry: implications in drug discovery and development, Epitheorese Klin. Farmakol. Farmakokinet. 11(2-3): 104-107 (1997)
Publication Date 1997
Full Text Language English
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Keywords Combinatorial chemistry, drugs.
Other Terms review article
Summary Combinatorial chemistry is having a major impact on the design and implementation of drug discovery programmes throughout the pharmaceutical and agrochemical industries. Rapid advances have already been made in the variety of chemical transformations now practicable on the solid phase. Combinatorial chemistry is a powerful tool that has radically altered the way in which large numbers of diverse compounds can be produced. The development of this technique and its implications in drug discovery are discussed.
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