Τόμος 16 (2002) – Τεύχος 2 – Άρθρο 2 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 16 (2002) – Issue 2 – Article 2 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Department of Pharmacology, Medical Faculty, University of Kragujevac, Serbia, Serbia and Montenegro

Accepted for publication: 1 June 2002

pharmakonpress[at]pharmakonpress[.]gr

2.  Monaghan D.T., ßridges R.J., Cotman C.W.: The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu. Rev. Pharmacol. Toxicol. 29: 365-402 (1989)

3.  Hollmann M., O’Shea-Greenfield A., Rogers S.W., Heinemann S.: Cloning by functional expression of a member of the glutamate receptor family. Nature 342: 643- 648 (1989)

4.  Houamed K.M., Kuijper J.L., Gilbert T.L., et al: Cloning, expression and gene structure of a G-protein coupled glutamate receptor from rat brain. Science 252: 1318-1321 (1991)

5.  Masu M., Tanabe Y., Tsuchida K., Shigemoto R., Nakanishi S.: Sequence and expression of a metabotropic glutamate receptor. Nature 349: 760-765 (1991)

6.  Torgner I., Kvamme E.: Synthesis of transmitter glutamate and the glial-neuron interrelationship. Mol. Chem. Neuropathol. 12: 11-17 (1990)

7.   Danbolt N.C.: Glutamate uptake. Prog. Neurobiol. 65: 1- 105 (2001)

8.  Fonnum F.: Glutamate, a neurotransmitter in mammalian brain. J. Neurochem. 42: 1-11 (1984)

9.  Baethmann A., Maier-Hauff K., Kempski O., Unterberg A., Wahl M., Schürer L.: Mediators of brain edema and secondary brain damage. Crit. Care. Med. 16: 972-978 (1988)

10.            Attwell D., Barbour B., Szatkowski M.: Nonvesicular release of neurotransmitter. Neuron 11: 401-407 (1993)

11. Fykse E.M., Fonnum F.: Amino acid neurotransmission: dynamics of vesicular uptake. Neurochem. Res. 21: 1053- 1060(1996)

12.            Bergles D.E., Diamond J.S., Jahr C.E.: Clearance of glutamate inside the synapse and beyond. Curr. Opin. Neurobiol. 9: 293-298 (1999)

13.            Baethmann A., Maier-Hauff K., Schürer L., et al: Release of glutamate and of free fatty acids in vasogenic brain edema. J. Neurosurg. 70: 578-591 (1989)

14.            Seal R.P., Amara S.G.: Excitatory amino acid transporters: a family in flux. Annu. Rev. Pharmacol. Toxicol. 39: 431-456(1999)

15.            Conti F., Weinberg R.J.: Shaping excitation at glutamatergic synapses. Trends Neurosci. 22: 451-458 (1999)

16.            van Rossum D., Hanisch U.K.: Cytoskeletal dynamics in dendritic spines: direct modulation by glutamate receptors? Trends Neurosci. 22: 290-295 (1999)

17. Cleland T.A.: Inhibitory glutamate receptors channels. Mol. Neurobiol. 3: 97-136 (1996)

18.            Ozawa S., Kamiya H., Tsuzuki K.: Glutamate receptors in the mammalian central nervous system. Prog. Neurobiol. 54: 581-618 (1998)

19.            Dingledine R., Borges K., Bowie D., Traynelis S.F.: The glutamate receptor ion channels. Pharmacol. Rev. 57: 7-61 (1999)

20.            Chittajaliu R., Braithwaite S.P., Vernon R.J., Clarke V.R.J., Henley J.M.: Kainate receptors: subunits, synaptic localization and function. Trends Pharmacol. Sci. 20: 26-35 (1999)

21.            Nakanishi S.: Molecular diversity of glutamate receptors and implication for brain function. Science (Wash. DC) 258: 597-603 (1992)

22.            Seeburg P.H.: The TINS/TiPS Lecture. The molecular biology of mammalian glutamate receptor channels. Trends Neurosci. 16: 359-365 (1993)

23.            Hollman M., Heinemann S.: Cloned glutamate receptors. Annu. Rev. Neurosci. 17: 31-108 (1994)

24.            Nishi M., Hinds H., Lu H.P., Kawata M., Hayashi Y.: Motoneuron-specific expression of NR3B, a novel NMDA- type glutamate receptor subunit that works in a dominant- negative manner. J. Neurosci. 21: 1-6 (2001)

25.            Villmann C., Strutz N., Morth T., Hollmann M.: Investigation by ion channel domain transplantation of rat glutamate receptor subunits, orphan receptors and a putative NMDA receptor subunit. Eur. J. Neurosci. 11: 1765-1778(1999)

26.            Ziff E.B.: Recent excitement in the ionotropic glutamate receptor. Ann. N. Y. Acad. Sci. 68: 465-473 (1999)

27.            Conn P.J., Pin J.P.: Pharmacology and function of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol. 37: 205-237 (1997)

28.            Schoepp D.D.: Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J. Pharmacol. Exp. Ther. 299: 12-20 (2001)

29.            Bleakman D., Lodge D.: Neuropharmacology of AMPA and kainate receptors. Neuropharmacology 37: 1187-1204 (1998)

30.            Bordi F., Ugotini A.: Group I metabotropic glutamate receptors: implications for brain diseases. Prog. Neurobiol. 59: 55-79 (1999)

31.            Schoepp D.D., Jane D.E., Monn J.A.: Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38: 1431-1476 (1999)

32.            Gasparini F., Kuhn R., Pin J.P.: Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives. Curr. Opln. Pharmacol. 2: 43-49 (2002)

33.            Storck T., Schulte S., Hofmann K., Stoffel W.: Structure, expression and functional analysis of Na⁺-dependent glutamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. USA 89: 10955-10959 (1992)

34.            Pines G., Danbolt N.C., Bjoras M., et al. Cloning end expression of a rat L-glutamate transporter. Nature 360: 464-467 (1992)

35.            Kanai Y., Hediger M.A.: Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360: 467-471 (1992)

36.            Masson J., Sagné., Hamon M.t El Mestikawy S.: Neurotransmitter transporters in the central nervous system. Pharmacol. Rev. 51: 439-464 (1999)

37.            Bergles D.E., Jahr C.E.: Synaptic activation of glutamate transporters in hippocampal astrocytes. Neuron 19: 1297-1308 (1997)

38.            Lehre K.P., Danbolt N.C.: The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification In young adult rat brain. J. Neurosci. 18: 8751-8757 (1998)

39.            Herzog E., Bellenchi G.C., Gras C., et al.: The existence of a second vesicular glutamate transporter specifies subpopulations of glutamatergic neurons. J. Neurosci. 21: 1-6 (2001)

40.            Collingridge G.L., Singer W.: Excitatory amino acid receptors and synaptic plasticity. Trends Pharmacol. Sci. 11: 290-296 (1990)

41.            Green J.G., Greenamyre J.T.: Bioenergetics and glutamate excitotoxicity. Prog. Neurobiol. 48: 613-634 (1996)

42.            Blandini F., Greenamyre J.T.: Prospectus of glutamate antagonists in the therapy of Parkinson’s disease. Fundam. Clin. Pharmacol. 12: 4-12 (1998)

43.            Marinelli S., Gatta F., Sagratella S.: Effects of GYKI 52466 and some 2,3-benzodiazepine derivatives on hippocampal in vitro basal neuronal excitability and 4- aminopyridine epileptic activity. Eur. J. Pharmacol. 391: 75- 80 (2000)

44.            Swanson C.J., Kalivas P.W.: Regulation of locomotor activity by metabotropic glutamate receptors in the nucleus accumbens and ventral tegmental area. J. Pharmacol. Exp. Ther. 292: 406-414 (2000)

45.            Sillevis Smitt P., Kinoshita A., De Leeuw B., et al.: Paraneoplastic cerebellar ataxia due to autoantibodies against a glutamate receptor: N. Engl. J. Med. 342: 21-27 (2000)

46.            Tamminga C.: Glutamatergic aspects of schizophrenia. Br. J. Psychiatry. Suppl. 37: 12-15 (1999)

47.            Vandergriff J., Rasmussen K.: The selective mGlu2/3 receptor agonist LY354740 attenuates morphine- withdrawal-induced activation of locus coeruleus neurons and behavioral signs of morphine withdrawal. Neuropharmacology 38: 217-222 (1999)

48.            Fürst S.: Transmitters involved in antinociception in the spinal cord. Brain Res. Bull. 48: 129-141 (1999)

49.            Coggeshall R.E., Carlton S.M.: Evidence for an inflammation-induced change in the local glutamatergic regulation of postganglionic sympathetic efferents. Pain 83: 163-168 (1999)

50.            Brandstätter J.H., Koulen P., Wässle H.: Diversity of glutamate receptors in the mammalian retina. Vision Res. 38: 1385-1397 (1998)

51.            Puel J.L.: Chemical synaptic transmission in the cochlea. Prog. Neurobiol. 47: 449-476 (1995)

52.            Chaudhari N., Landin A.M., Roper S.D.: A metabotropic glutamate receptor variant functions as a taste receptor. Nat. Neurosci. 3: 113-119 (2000)

53.            Jia C., Chen W.R., Shepherd G.M.: Synaptic organization and neurotransmitters in the rat accessory olfactory bulb. J. Neurophysiol. 81: 345-355 (1999)

54.            Aylwin M.L., Horowitz J.M., Bonham A.C.: NMDA receptors contribute to primary visceral afferent transmission in the nucleus of the solitary tract. J. Neurophysiol. 77: 2539-2548 (1997)

55.            Niwa M., Taniyama K.: Central autonomic mechanism and neurotransmitters. Nippon Rinsho 50: 680-685 (1992)

56.            Zhang W., Mifflin S.W.: Excitatory amino-acid receptors contribute to carotid sinus and vagus nerve evoked excitation of neurons in the nucleus of the tractus solitarius. J. Auton. Nerv. Syst. 55: 50-56 (1995)

57.            Haji A., Pierrefiche 0„ Foutz A.S., Champagnat J., Denavit Saubie M., Takeda R.: Pharmacological properties of peripherally induced postsynaptic potentials in bulbar respiratory neurons of decerebrate cats. Neurosci. Lett. 211: 17-20(1996)

58.            Khan A.M., Curräs M.C., Dao J., et al.: Lateral hypothalamic NMDA receptor subunits NR2A and/or NR2B mediate eating: immunochemical/behavioral evidence. Am. J. Physiol. 276: R880-891 (1999)

59.            Chambille I.: Circadian rhythm of AMPA receptor GluR2/3 subunit-immunoreactivity in the suprachiasmatic nuclei of Syrian hamster and effect of a light-dark cycle. Brain Res. 833. 27-38 (1999)

60.            Eylgor O., Jennes L.: Kainate receptor subunit-positive gonadotropin-releasing hormone neurons express c-Fos during the steroid-induced luteinizing hormone surge in the female rat. Endocrinology 141: 779-786 (2000)

61.            Ishio S., Yamada H., Craft C.M., Moriyama Y.: Hydroxyindole-O-methyltransferase is another target for L- glutamale-evoked inhibition of melatonin synthesis in rat pinealocytes. Brain Res. 850: 73-78 (1999)

62.            Sivarao D.V., Krowicki Z.K., Abrahams T.P., Hornby, P.J.: Vagally-regulated gastric motor activity: evidence for kainate and NMDA receptor mediation. Eur. J. Pharmacol. 368: 173-182 (1999)

63.            Llewellyn-Smith I.J., Arnolda L.F., Piiowsky P.M., Chalmers J.P., Minson J.B.: GABA- and glutamate- immunoreactive synapses on sympathetic preganglionic neurons projecting to the superior cervical ganglion. J. Auton. Nerv. Syst. 71: 96-110(1998)

64.            Gill S.S., Pulido O.M., Mueller R.W., McGuire P.F.: Immunochemical localization of the metabotropic glutamate receptors in the rat heart. Bratn Res. Bull. 48: 143-146 (1999)

65.            Kirchgessner A.L.: Glutamate in the enteric nervous system. Curr. Opin. Pharmacol. 1: 591-596 (2001)

66.            Hu H.Z., Ren J., Liu S., Gao C., Xia Y., Wood J.D.: Functional group I metabotropic glutamate receptors in submucous plexus of guinea-pig ileum. Br. J. Pharmacol. 122: 1631-1635 (1999)

67.            Ren J., Hu H.Z., Liu S., Xia Y., Wood J.D.: Glutamate receptors in the enteric nervous system: ionotropic or metabotropic?. Neurogastroenterol. Mol. 12: 257-264 (2000)

68.            Jankovic S.M., Milovanovic D., Matovic M., Iric Cupic V.: The effects of excitatory amino acids on isolated gut segments of the rat. Pharmacol. Res. 39: 143-148 (1999)

69.            Sinsky M., Donnerer J.: Evidence for a neurotransmitter role of glutamate in guinea pig myenteric plexus neurons. Neurosci. Lett. 258: 109-112 (1998)

70.            Perl T.M., Bedard L., Kosatsky T., Hockin J.C., Todd E.C.D., Remis R.S.N.: An outbreak of toxyc encephalopathy caused by eating mussels contaminated with domoic acid. N. Engl. J. Med. 322: 1775-1780 (1990)

71. Milovanovic D.R.: The effects of excitatory amino acids on smooth muscles of digestive tract. P.h.D. Thesis. University of Kragujevac, Medical Faculty, Kragujevac, 2001

72.            Skerry T.M., Genever P.G.: Glutamate signaling in non-neuronal tissues. Trends Pharmacol. Sci. 22: 174-181 (2001)

73.            Meldrum B.S.: Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J. Nutr. 130: 1007S-1015S (2000)

74.            Grlron I., Max M.B., Lee G. et al.: Effects of the 2-amino-3-hydroxy-5-methyl-4-isoxazole-proprionic acid/kainate antagonist LY293558 on spontaneous and evoked postoperative pain. Clin. Pharmacol. Ther. 68: 320-327 (2000)

pharmakonpress[at]pharmakonpress[.]gr

pharmakonpress[at]pharmakonpress[.]gr