Τόμος 15 (2001) – Τεύχος 3 – Άρθρο 14 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 15 (2001) – Issue 3 – Article 14 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Department of Experimental Pharmacology, Medical School, University of Athens

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2.    Delves P.J., Roitt I.M. (2000): The immune system. Second of two parts. N. Engl, J. Med., 343, 108-117.

3.    Roitt I.M.: Essential Immunology, 9th Ed, Blackwell Science, Oxford, 1997

4.    Nemazee D.: Receptor selection in B and T lymphocytes. Ann. Rev. Immunol. 18: 19-51 (2000)

5.    Farber D.L.: T cell memory: heterogeneity and mechanisms. Clin. Immunol. 95: 173-181 (2000)

6.    Sakaguchi S.: Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101: 455-458 (2000)

7.    Rook G.A., Hernandez-Pando R., Lightman S.L.: Hormones, peripherally activated prohormones and the regulation of the TH1/TH2 balance. Immunol. Today 15: 301-303 (1994)

8.    Knapp W., Dorken B., Gilks W.R., Rieber E.P., Schmidt R.E., Stein H., von dem Borne A.E.G.K.: CD Guide. In Leukocyte typing IV. Oxford University Press, Oxford, New York, Tokyo, pp. 1074-1093, 1989

9.    Middleton E.,Jr.: Effect of plant flavonoids on immune and inflammatory cell function. Adv. Exp. Med. Biol. 439: 175-182 (1998)

10.  Middleton E.Jr., Kandaswami, C.: Effects of flavonoids on immune and inflammatory cell functions. Blochem. Pharmacol. 43: 1167-1179 (1992)

11.  Hirano T, Gotoh M., Oka K.: Natural flavonoids and ligands are potent cytostatic agents against human leukemic HL-60 cells. Life Sci. 55: 1061-1069 (1994)

12.  You K.M., Son K.H., Chang H.W., Kang S.S., Kim H.P.: Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro. Planta Med. 64: 546-550 (1998)

13.  Bouic P.J., Lamprecht J.H.: Plant sterols and sterolins: a review of their immune-modulating properties. Altern. Med. Rev. 4: 170-177 (1999)

14.  Hirano T., Oka K., Kawashima E., Akiba M.: Effects of synthetic and naturally occuring flavonoids on mitogen- induced proliferation of human peripheral-blood lymphocytes. Life Sci. 45: 1407-1441 (1989)

15.  Namgoong S.Y., Son K.H., Chang H.W., Kang S.S., Kim H.P.: Effects of naturally occurring flavonoids on mitogen-induced lymphocyte proliferation and mixed lymphocyte culture. Life Sci. 54: 313-320 (1993)

16.  Lee S.J., Choi J.H., Son K.H., Chang H.W., Kang S.S., Kim H.P.: Suppression of mouse lymphocyte proliferation in vitro by naturally-occurring biflavonoids. Life Sci. 57: 551- 558(1995)

17.  Cho J.Y., Kim P.S., Park J., Yoo E.S., Baik K.U., Kim Y., Park M.H.: Inhibitor of tumor necrosis factor-alpha production in lipopolysaccharide-stimulated RAW264.7 cells from Amorpha fruticosa. J. Ethnopharmacol. 70: 127-133 (2000)

18.  Yoffey J.M., Winter G.C.B., Osmond D.G., Meek E.S.: Morphological studies in the culture of human leucocytes with phytohaemagglutinin. Br. J. Haematol. 11: 488-492 (1965)

19.  Rabatic S., Dekaris D.: Simple phase-contrast microscopy test for human lymphocyte transformation induced by mitogens or antigens. Acta Med. Jug. 33: 363-372 (1979)

20.  Barch M.J.: The ACT Cytogenetics Laboratory Manual, Raven Press, pp. 17-23, New York, 1991

21.  Price D.J., Timson J.: Temporal variation in mitotic index of phytohaemagglutinin stimulated human lymphocytes. Acta Haematol. 46: 321-325 (1971)

22.  Sfikakis P.P., Souliotis V.L., Akbar A., Katsiiambros N., Hoffbrand V.A., Panayiotidis P.: Regulation of bcl-2 and fas expression in primary N. activation of human peripheral lymphocytes is not sensitive to dexamethasone or cyclosporin-A. Hum. Immunol. 50: 121-126 (1996)

23.  Misheil B.B., Shiigi S.M.: Selected Methods in Cellular Immunology, W.H. Freeman and Company, p. 16 San Francisco, 1980

24.  Ferriola P.C., Cody V., Middleton E. Jr.: Protein kinase C inhibition by plant flavonoids. Kinetic mechanisms and structure-activity relationships. Biochem. Pharmacol. 38: 1617-1624 (1989)

25.  Agullo G., Gamet-Payrastre L., Manenti S., Viala C., Remesy C., Chap FI., Payrastre B.: Relationship between fiavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition. Biochem. Pharmacol. 53: 1649-1657 (1997)

26.  Cushman M., Nagarathnam D., Burg D.L., Geahlen R.L.: Synthesis and protein-tyrosine kinase inhibitory activities of flavonoid analogues. J. Med Chem. 34: 798-806 (19910

27.  Wei Y.Q., Zhao X., Kariya Y., Fukata FI., Teshigawara K., Uchida A.: induction of apoptosis by quercetin: involvement of heat shock protein. Cancer Res. 54: 4952-4957 (1994)

28.  Markovits J., Lrnassier C., Fosse P., Couprie J., Pierre J., Jacquemin-Sablon A., Saucier J.M., Le Peck J.B., Larsen A.K.: Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II. Cancer Res. 49: 5111-5117 (1989)

29.  Austin C.A., Patel S., Ono K., Nakane H., Fisher L.M.: Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives. Biochem. J. 282: 883-889 (1992)

30.  Plaumann B., Fritsche M., Rimpier K, Brandner G., Hess R.D.: Flavonoids activate wild-type p53. Oncogene 13: 1605-1614 (1996)

31.  Jacobsen K.A., Prasad V.S., Sidman C.L., Osmond D.G.: Apoptosis and macrophage-mediated deletion of precursor B cells in the bone marrow of E mu-myc transgenic mice. Blood 84: 2784-2794 (1994)

32.  Kuo S.M.: Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells. Cancer Lett. 110: 41-48(1996)

33.  Konig A., Schwartz G.K., Mohammad R.M., Al-Katib A., Gabrilove J.L.: The novel cyclin-dependent kinase inhibitor flavopiridol downregulates Bcl-2 and induces growth arrest and apoptosis in chronic B-cell leukemia lines. Blood 90: 4307-4312 (1997)

34.  Huang Y.T., Hwang J.J., Lee P.P., Ke F.C., Huang J.H., Huang C.J., Kandaswami C., Middleton E. Jr,, Lee M.T.: Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor. Br. J. Pharmacol. 128: 999-1010 (1999)

35.  Taga K., Yoshida M., Kaneko M., Asada M., Okada M., Taniho M., Tosato G.: Contribution of automated hematology analysis to the detection of apoptosis in peripheral blood lymphocytes. Cytometry 42: 209-214 (2000)

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