| Title | In vivo evaluation of the effect of β-cyclodextrin on sebum secretion in people developing two kinds of acne vulgaris: a. comedonal acne and b. cosmetic acne | |
| Authors | Vassiliki K. Kefala¹ and Paraskevi Kinigalaki²
1. Technological Educational Institution. Faculty of Health and Caring Professions, Egaleo Athens, Greece 2. University of Athens, School of Pharmacy, University Campus Zografou, Athens, Greece |
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| Citation | Kefala, V.K., Kinigalaki, P.: In vivo evaluation of the effect of β-cyclodextrin on sebum secretion in people developing two kinds of acne vulgaris: a. comedonal acne and b. cosmetic acne, Epitheorese Klin. Farmakol. Farmakokinet. 16(3): 179-182 (2002) | |
| Publication Date | Received for publication: 1 July 2002
Accepted for publication: 14 November 2002 |
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| Full Text Language | English | |
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| Keywords | β-Cyclodextrin, acne vulgaris, sebum, comedonal acne, cosmetic acne. | |
| Other Terms | review article | |
| Summary | The effect of medicines and cosmetics on people showing acne has been studied by many researchers. The application of AHA either as such or in the form of inclusion complexes, which ensures controlled release of glycolic acid, constitutes certainly a novelty. Sebum secretion in people with comedonal acne and cosmetic acne – two kinds of acne vulgaris – considerably decreased following application of cosmetics containing β-cyclodextrins. This paper examines in vivo changes in sebum secretion on the skin of volunteers after application of cosmetic products containing (β-cyclodextrin, records the results and proceeds to their statistical analysis. Sebum plays a role in the overall pathogenesis of the disease because sebum is comedogenic, causes inflammation when injected into skin, and acne can be controlled by factors which inhibit sebaceous glands. | |
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