Τόμος 20 (2006) – Τεύχος 1 – Άρθρο 5 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 20 (2006) – Issue 1 – Article 5 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Stress and the progression of HIV disease
Authors Penelope A. Avagianou¹, Stelios M. Piperakis² and Maria Zafiropoulou¹

1.      Laboratory of Developmental Psychology and Psychopathology

2.     Biology Unit, Pre-school Education Department, University of Thessaly, Volos, Greece

Citation Avagianou, P.A., Piperakis, S.M., Zafiropoulou, M.: Stress and the progression of HIV disease, Epitheorese Klin. Farmakol. Farmakokinet. 20(1): 38-42 (2006)
Publication Date Accepted for publication (Final version): 15 April 2006
Full Text Language English
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Keywords Stress, HIV, PNI, immunology.
Other Terms review article
Summary The reciprocal interactions between the neuroendocrine, immune, and autonomic nervous system are complicated, yet worthy of examination. A body of literature suggests that psychological factors such as stress, or psychiatric conditions such as major depression, may influence the immune system thereby altering host susceptibility to viral, or other types of infection.  The present article examines the role of stress in the progression of HIV disease. We refer to the immune system, to stress, HIV, psychosocial factors well as the impact of psychiatric conditions like depression. In particular, we discuss about the biological mediators of psychological status which can play an important role in mediating HIV disease progression. We evaluate the most recent literature within the context of this burgeoning field, taking into account some methodological problems that often arise. Some considerations for future research are also presented at the end.
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