| Title | Prevention and delaying of type 2 diabetes mellitus through exercise and nutrition | |
| Author | Spyridon Dimoschakis
Department of Ergometry, Sports Unit, Hellenic Parliament, Athens, Hellas |
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| Citation | Dimoschakis, S.: Prevention and delaying of type 2 diabetes mellitus through exercise and nutrition, Epitheorese Klin. Farmakol. Farmakokinet. 23(3): 153-156 (2009) | |
| Publication Date | Accepted for publication (Final Version): July 1, 2009 | |
| Full Text Language | English | |
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| Keywords | Type 2 diabetes mellitus, pathophysiology, prevention, lifestyle modification, exercise, natural products. | |
| Other Terms | review article | |
| Summary | Diabetes mellitus (DM) is a chronic metabolic disorder marked by hyperglycemia. Type 2 diabetes mellitus (T2DM) results from insulin resistance, with inadequate insulin secretion to sustain normal metabolism. Common complications of T2DM are eye, kidney and nerve diseases, as well as an increased risk for the development of cardiovascular disease and cancer. Poor lifestyle choices, as obesity and lack of physical activity, are responsible for the development of T2DM. Although obesity once served as a surrogate marker for the risk of T2DM, we know now that excess adipose tissue secretes inflammatory cytokines that left unchecked, accelerate the progression to insulin resistance and T2DM. The basic targets in the treatment of T2DM are the normalization of blood glucose levels, blood pressure control and lipid management. The means for the prevention and treatment of T2DM are lifestyle interventions, such as dietary modification and/or exercise training and have been shown to improve glucose homeostasis, but may not normalize the disease process unless weight loss is achieved and increased physical activity patterns are established the right nutrition, weight loss and increased physical activity. Furthermore, utilization of natural products may serve as a significant adjunct in the fight against insulin resistance, but further research is needed to ascertain their validity. | |
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Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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