| Title | Application of the Taguchi approach in laboratory practice: preliminary results on an evaluation experiment | |
| Authors | Rozina Vavetsi¹,², Chrysanthi Papaanastasopoulou¹, Georgia Dougekou¹, George J. Besseris² and Nikolaos M. Sitaras¹1. Department of Pharmacology, School of Medicine, University of Athens,
2. Postgraduate programme in Quality Management, T.E.I Piraeus/University of Paisley, Scotland |
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| Citation | Vavetsi, R., Papaanastasopoulou, C., Dougekou, G., Besseris, G.J., Sitaras, N.M.: Application of the Taguchi approach in laboratory practice: preliminary results on an evaluation experiment, Epitheorese Klin. Farmakol. Farmakokinet. 20(2): 122-124 (2006) | |
| Publication Date | Accepted for publication: 19-20 May 2006 | |
| Full Text Language | English | |
| Order – Buy | Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €) pharmakonpress[at]pharmakonpress[.]gr | |
| Keywords | Glycosaminoglycans, nails, extraction, robust design. | |
| Other Terms | review article | |
| Summary | Laboratory protocols often show complexity due to the fact that a) more than one parameter affects the desirable outcome and b) unknown interactions between certain parameters exist. To encounter such phenomena in biomedical research a novel experimental technique, the Taguchi robust design methodology has been successfully applied the last decade. The aim of the present study is the evaluation of the Taguchi method in finding the best combination of experimental parameters that guarantee for the highest glycosaminoglycan yield extracted from nails. | |
| References | 1. Akhoudoli G.A., Porter I.M., Julian Blow J., Swedlow J.R.: Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach. Proteome Sci. 2: 6 (2004)2. Jenny C., Dobay O., Lengyel A., Adam E., Nasz I.: Taguchi optimisation of ELISA procedures. J. Immunol. Meth. 223: 137- 146 (1999)
3. Morsi H., Yong K.L., Jewell A.P.: Evaluation of the Taguchi methods for the simultaneous assessment of the effects of multiple variables in the tumour microenvironment. Int. Sem. Surg. Oncol. 1: 7 (2004) 4. Carney C.L, Muir H.: The structure and function of cartilage proteoglycans. Physiol. Rev. 68: 858-910 (1988) 5. Eggen H.K., Sorensen T., Kolsen O.S., Pedersen E.M.: Sulphated glycosaminoglycans and collagen in two bovine muscles (M. Semitendinosus and M. Psoas Major) different in texture. J. Agrtic. Food Chem. 47: 1445-1452 (1999) 6. Skandalis S.S, Theocharis A.D., Vynios D.H., Theocharis D.A., Papageorgacopoulou N.: Proteoglycans in human cartilage. Identification of proteoglycan types in successive cartilage extracts with particular reference to aggregating proteoglycans. Biochimie 86: 221-229 (2004) 7. Barret J.A, Buttle J.D., Farndale R.W.: Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim. Biophys. Acta 883: 173-177 (1986) 8. Madhav P.S.: Quality Engineering Using Robust Design. P. 67, 1987 |
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| Relative Papers |
Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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| ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 2006 – ANNUAL SUBSCRIPTION 2006 | |
| Γλώσσα Πλήρους Κειμένου – Full Text Language | Αγγλικά – English |
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