Τόμος 24 (2010) – Τεύχος 2 – Άρθρο 58 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 24 (2010) – Issue 2 – Article 58 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Coagulation factors changes induced by stress and saturated lipid diet
Authors Antonia Kotsiou, Akaterini Pitsicali and Christine Tesseromatis

Department of Pharmacology, Medical School, University of Athens, Greece

Citation Kotsiou, A., Pitsicali, A., Tesseromatis, C.: Coagulation factors changes induced by stress and saturated lipid diet, Epitheorese Klin. Farmakol. Farmakokinet. 24(2): 158-160 (2010)
Publication Date 2010
Full Text Language English
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Keywords stress, saturated fats, coagulation factors.
Other Terms Review article
Summary Coagulation factors are associated with lipid profile. Chronic stress is reported to promote the risk for atherothrombotic disease with increase in the coagulation activity.The aim of the study was, to assess in an experimental model of swimming stress in association to diet rich in saturated fat (butter), the  serum coagulation factors such as prothrombine time, activated partial thromboplastin time (a-ptt), fibrinogen, protein C, antithrombine III and plasminogen. Stress and saturated fat diet increased Fibrinogen and Antithrombine III and lowered protein C levels. Ιt may be concluded that saturated lipid diet under stress is negatively correlated with coagulation process and predisposes to thromboembolic disease.
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