| Title | Modulation of P-glycoprotein mediated drug transport in caco-2 cells by aloe vera phytotherapeutic products: a methodology to evaluate drug-herb interactions in clinical practice | ||
| Authors | Marios Spanakis, Ioannis S. Vizirianakis and Ioannis Niopas
Laboratory of Pharmacology, Department of Pharmaceutical Sciences, Aristotle University, Thessaloniki, Greece |
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| Citation | Spanakis, M., Vizirianakis, S., Niopas, I.: Modulation of P-glycoprotein mediated drug transport in caco-2 cells by aloe vera phytotherapeutic products: a methodology to evaluate drug-herb interactions in clinical practice, Epitheorese Klin. Farmakol. Farmakokinet. 24(2): 211-213 (2010) | ||
| Publication Date | 2010 | ||
| Full Text Language | English | ||
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| Keywords | Drug-herb interactions, aloe vera, caco-2, P-gp, rhodamine-123. | ||
| Other Terms | Review article | ||
| Summary | Nowadays, drug-herb interactions are considered as a potential factor affecting pharmacotherapy outcomes. In this work we evaluated the modulation of P-gp function by Aloe vera juice in Caco-2 cells. The data obtained thus far indicated that Aloe vera exhibited the capability to inhibit P-gp thus raising the possibility of the emergence of adverse drug reactions (ADRs). | ||
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| Relative Papers | |||
Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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| ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 2010 – ANNUAL SUBSCRIPTION 2010 | |
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