Title | Effects of long-term antipsychotic treatment of oxidative defense system parameters | ||
Authors | K. Kosma¹, A. Sianni¹, K. Liatsos², C. Leotsakou¹, A. Kalogeropoulou¹ and V. Roumpos¹
1. Dromokaitio Psychiatric Hospital, Athens, Greece 2. Mitera Maternity Hospital, Athens, Greece |
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Citation | Kosma, K., Sianni, A., Liatsos, K., Leotsakou, C., Kalogeropoulou, A. et al.: Effects of long-term antipsychotic treatment of oxidative defense system parameters, Epitheorese Klin. Farmakol. Farmakokinet. 22(2): 195-197 (2008) | ||
Publication Date | 23-25 May 2008 | ||
Full Text Language | English | ||
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Keywords | Oxidative defense system, neuronal damage, conventional antipsychotics, atypical antipsychotics. | ||
Other Terms | Review article | ||
Summary | The results of many recent studies are indicative of an impaired antioxidant defense system in a number of psychiatric conditions, and furthermore this alteration has often been postulated as a possible mechanism for neuronal damage. However, it is not clear yet whether this is due to the pathophysiology of the illness or is a result of medication. The present study aimed to examine the effect of long-term antipsychotic treatment and furthermore to record if any differences exist between conventional and atypical antipsychotics with regard to the examined factors. As it was proven, long-term administration of conventional and atypical antipsychotics may produce similar effects in the antioxidant defense system of all patients, regardless the diagnosis. | ||
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Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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