| Title | Evaluation of the bioequivalence of two isotretinoin products in capsules (20 mg/cap) in healthy volunteers | |
| Authors | Aggeliki Karountzou¹, Chrisovaladou Tsoukia¹, Georgios Adamis³, Maria Kounoukla¹, Panagiota Katsimpra¹, Eleftheria Karatza¹, Maria Tsalta¹, Nikolaos Karagiannides¹ and Michael Koupparis²1. Mentor Laboratories S.A. Spaton Avenue 197, Pallini, Attiki, Greece
2. Laboratory of Analytical Chemistry, Department of Chemistry, University of Athens 3. General National Hospital of Athens G. Gennimatas, 1st Internal Medicine Dept, Athens, Greece |
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| Citation | Karountzou, A., Tsoukia, Ch., Adamis, G., Kounoukla, M., Katsimpra, P. et al: Evaluation of the bioequivalence of two isotretinoin products in capsules (20 mg/cap) in healthy volunteers, Epitheorese Klin. Farmakol. Farmakokinet. 20(2): 223-225 (2006) | |
| Publication Date | Accepted for publication: 19-20 May 2006 | |
| Full Text Language | English | |
| Order – Buy | Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €) pharmakonpress[at]pharmakonpress[.]gr | |
| Keywords | Isotretinoin and 4-oxo-isotretinoin determination, male volunteers, bioequivalence. | |
| Other Terms | review article | |
| Summary | An efficient liquid chromatographic method, with ultraviolet spectrometric detection, using acitretin as internal standard is described for the determination of Isotretinoin in male healthy volunteers. The comparison of the results among two preparations demonstrated that these are bioequivalent. | |
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Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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