Τόμος 25 (2011) – Τεύχος 3 – Άρθρο 2 – Review of Clinical Pharmacology and Pharmacokinetics-Διεθνής Έκδοση – Volume 25 (2011) – Issue 3 – Article 2 – Review of Clinical Pharmacology and Pharmacokinetics -International Edition

Title Interactions of energy drinks with alcohol
Authors Evgenia Petala, Ioannis Kapsokalivas and Maria Mironidou Tzouveleki

A’ Laboratory of Pharmacology, Medical School, Aristotle’s University, Thessaloniki, Hellas

Citation Petala, E., Kapsokalivas, I., Mironidou-Tzouveleki, M.: Interactions of energy drinks with alcohol, Epitheorese Klin. Farmakol. Farmakokinet. 25(3): 125-129 (2011)
Publication Date Accepted for publication: November 10, 2011
Full Text Language English
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Keywords Energy, drinks, caffeine, taurine, alcohol, drug interactions.
Other Terms review article
Summary In recent years, consumption of so called energy drinks among young people, especially students and athletes has been increased in a steady manner. Energy drinks contain many natural substances, vitamins, minerals and herbals. We know little about their interactions with drugs and other substances. The aim of this study is to present the available data about the interactions between various substances of energy drinks and alcohol. There is a dose-dependent interaction between energy drinks and ethanol. There are indications that taurine that is contained in the energy drinks generally has a stimulating action and probably inhibits the suppressing effects of alcohol but stronger evidence is required. Caffeine has inhibiting action against the suppressing effect of alcohol only in small amounts. The combination of caffeine or taurine with alcohol is also diuretic and can lead to severe dehydration. Interactions are also mentioned between ginseng and alcohol. The small number of related studies reveals the need of more clinical trials in humans to examine the safety of simultaneous consumption of energy drinks and alcohol.
References 1. Safe food: A review of the health effects of stimulant drinks.  http://www.safefood.eu/Global/Publications/Research%20reports/FSPB%20Stimulant%20drinks%20.pdf?epslanguage=en (18.2.2011)

2.  Henemann K., Zidenberg-Cherr S.: Some Facts about Energy Drinks. Nutrition and Health Info-Sheet. Depart-ment of Nutrition University of California, 2007

3. Reissig C, Strain E, Griffiths R.: Caffeinated energy drinks-a growing problem. Drug Alcohol Depend. 99: 1-10 (2009)

4. Health Psychology [Home Page on the internet]. Levy J.: Vanderbilt University. Energy drinks: potential performance enhancers or publicity hype. Nashville Tennesse, 2009. from:http://healthpsych.psy.vanderbilt.edu/2009/EnergyDrinks.htm

5. Kapner D.A.: Ephedra and energy drinks on college campuses. The Higher Education Center for Alcohol and Other Drug Abuse and Violence Prevention. 2008. from: http://www.higheredcenter.org/files/product/energydrinks.pdf

6. Ferreira S.E., de Mello M.T., Pompeia S., Souza-Formigoni M.L.O.: Effects of energy drink ingestion on alcohol intoxication. Alcohol Clin. Exp. Res. 30: 598-605 (2006)

7. Malinauskas B.M., Aeby G.V., Overton R.F., Carpenter-Aeby T., Barber-Heidal K.: A survey of energy drink consumption patterns among college students. Nutrition J. 6: 35 (2007)

8. Paddock R.: Energy drinks’ effects on student-athletes and implications for athletic departments. Sport J. 2008;11(4) from: http://www.thesportjournal.org/article/energy-drinks-effects-student-athletes-and-implications-athletic-departments.

9. European Union: Commission directive 2002/67/EC of 18 July 2002 on the labeling of foodstuffs containing quinine, and of foodstuffs containing caffeine. from: http://eurlex.europa.eu/LexUriServ/site/en/oj/2002/l_191/l_19120020719en00200021.pdf  (18. 2. 2011)

10. Health Canada. Safe use of energy drinks. Available from: http://www.hc-sc.gc.ca/iyh-vsv/alt_formats/cmcd-dcmc/pdf/energy-energie_e.pdf

11. Seifert S.M., Schaechter J.L., Hershorin E.R., Lipshultz S.E.: 2011. Health Effects of energy drinks on children, adolescents, and young adults. Pediatrics 127: 511-528 (2011)

12. Jacobson B.H., Kulling F.A.: Health and ergogenic effects of caffeine. Br. J. Sports Med. 23: 34-40 (1989)

13. Jullien R.M.: Βασικές αρχές ψυχοφαρμακολογίας. Pp. 248-258, 2η έκδοση, Πασχαλίδης, Αθήνα, 2003

14. Clauson K.A., Shields K.M., McQueen C.E., Persad N.: Safety issues associated with commercially available energy drink. Pharmacy Today 14(5): 52-64 (2008)

15. Myronidou-Tzouveleki Μ. and al. (eds).: Alcohol and CNS. 2nd Ed. University Studio Press, Thessaloniki, 2002 (n Greek)

16. Weldy D.: Risks of alcoholic energy drinks for youth. J. Am. Board Fam. Med. 23: 555-558 (2010) Available from: http://www.jabfm.org/cgi/content/full/23/4/555

17. Rush C.R., Higgins S.T., Hughes J.R., Bickel W.K., Wiegner M.S.: Acute behavioral and cardiac effects of alcohol and caffeine alone and in combination, in humans. Behav. Pharmacol. 4: 562-572 (1993)

18. Eynde F., Baelen P., Portzky M., Audenaert K.: The effects of energy drinks on cognitive performance. Tijdschr Psychiatr. 50: 273-281 (2008)

19. Liguori A., Robinson J.H.: Caffeine antagonism of alcohol-induced driving. Drug Alcohol Depend. 63: 123-129 (2001)

20. Gendle M., Smucker D., Stafstrom J., Helterbran M., Glazer K.: Attention and reaction time in university students following the consumption of Red Bull®. Open Nutr. J. 3: 8-10 (2009)

21. European Commission: Health and Consumer Protection. Opinion of the Scientific Committee on Food Additional Information on ‘energy’ drinks. March of 2003.

22. Quertemol E., Linotte S., De Witte S.: Differential taurine responsiveness to ethanol in high- and low-alcohol sensitive rats: a brain microdialysis study. Eur. J. Pharmacol. 444: 143-150 (2002)

23. Masur J., De Souza M., Laranjeira R., Zwicker A., Formigoni G.: Lack of effect of intravenous hyper tonic glucose on the intensity of alcohol intoxication induced experimentally and observed in patients of an emergency room. Pharmacology 26: 54-60 (1983)

24. Zacchia C., Pihl R., Young S., Ervin F.: Effect of sucrose consumption on alcohol-induced impairment in male social drinkers. Psychopharmacology (Berl)105: 49-56 (1991)

25. Roberts C., Robinson S.: Alcohol concentration and carbonation of drinks: the effect on blood alcohol levels. J. Forensic. Leg. Med. 14: 398-405 (2007)

26. Ferreira S., Quadros I., Trindade A., Takahashi S.O., Souza-Formigoni K.: Can energy drinks reduce the depressor effect of ethanol? An experimental study in mice. Physiol. Behavior.  82: 841-847 (2004)

27. Davis R.: Is this drug abuse. J. Health Resource Center: 28-30 (2005)

28. Ginsburg B., Lamb C.: Taurine and ethanol interactions: Behavioral effects in mice. Eur. J. Pharmacol. 578: 228–237 (2008)

29. Hussein S.: The effects of energy drinks. J. Health Resource Center 1: 3-6 (2002)

30. Ericson M., Molander A., Stomberg R., Söderpalm B.: Taurine elevates dopamine levels in the rat nucleus accumbens; antagonism by strychnine. Eur. J. Neurosci. 23: 3225-3229 (2006)

31. Curry K., Stasio M.J.: The effects of energy drinks alone and with alcohol on neuropsychological functioning. Hum. Psychopharmacol. Clin. Exp. 24: 473-481 (2009)

32. Coon J.T, Edzard E.: Panax ginseng: a systematic review of adverse effects and drug interactions. Drug Safety 25: 323-344 (2002)

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