Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Issue 1

Lutein is a xanthophyll carotenoid that can be found in a divergency of fruits and plants. Its main action is to protecteye health and vision. Its antioxidant properties play a crucial role in eye agitations, in decreasing inflammation, inprotecting the neural tissues from chemical analyzed hypoxia and cell apoptosis. Lutein supplementation inassociation with low-calorie diet had a notable abatement in fat-free mass, visceral fat and serum levels of totalcholesterol and LDL-cholesterol. Lutein may also have a natural anti-cancer effect. This is because foods rich in luteinhave antioxidant activity and oppose inflammation and oxidative stress. The benefits to the literature from this mini-review is that it has summarized the main actions of lutein in the human body. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Issue 1

In recent years, the study of medicinal plants’ therapeutic properties has increased due to their effects and biologicalactivities. The Acanthaceae family consists of 242 genera and 3947 species mainly distributed across tropical andsubtropical zones. This family is known to contain a wide range of bioactive compounds, such as, alkaloids, triterpenessteroids glycosides, polyphenols, and polysaccharides. Continue reading

Review of Clinical Pharmacology and Pharmacokinetics – International Edition – Volume 38 (2024) – Issue 1

Diabetes is a common and serious disease. However, the past 50 years have seen a growing ageing population withan increasing prevalence of type 2 diabetes mellitus (DM2). Now, nearly half of all individuals with diabetes mellitusare older adults (aged ≥65 years). Elderly people with diabetes is a heterogeneous group, in many cases the conditionof diabetes is accompanied by other chronic diseases, but also by the ability of the elderly themselves to control theirblood glucose. The therapeutic treatment of elderly diabetic patients must be done with special attention and a lot ofthought. Special importance should be given to exercise with aerobic exercise or alternatively the application of aprogram of progressive increase in muscle intensity (3-5 times a week), as well as training in proper nutrition withparticular emphasis on the Mediterranean diet, which seems to increase survival in adults. Continue reading

Τόμος 36 (2022) – Τεύχος 1 – Άρθρο 4 – Review of Clinical Pharmacology and Pharmacokinetics -Διεθνής Έκδοση – Volume 36 (2022) – Issue 1 – Article 4 – Review of Clinical Pharmacology and Pharmacokinetics – International Edition

Antioxidant Activity in Patients with Type II Diabetes Continue reading

Τόμος 37 (2023) – Τεύχος 2 – Άρθρο 6 – Review of Clinical Pharmacology and Pharmacokinetics -Διεθνής Έκδοση – Volume 37 (2023) – Issue 2 – Article 6 – Review of Clinical Pharmacology and Pharmacokinetics – International Edition

Parabens are esters of p-hydroxybenzoic acid and have been used as preservatives for personal care products, pharmaceuticals, cosmetics, and foods attributable to their anti-microbial and anti-fungal properties. Continue reading

Volume 37 (2023) – Issue 1 – Article 5 – Review of Clinical Pharmacology and Pharmacokinetics – International Edition

Diabetes mellitus refers to a group of diseases that affect how the body uses blood sugar (glucose). Glucose is an important source of energy for the cells that make up the muscles and tissues. It’s also the brain’s main source of fuel. Continue reading