Τόμος 34 (2020) – Τεύχος 1 –Άρθρο 2 – Review of Clinical Pharmacology and Pharmacokinetics – Διεθνής Έκδοση – Volume 34 (2020) – Issue 1 – Article 2 – Review of Clinical Pharmacology and Pharmacokinetics – International Edition
The heme enzyme soluble Guanylate Cyclase (sGC) is a pivotal amplification target in the NO-sGC-cGMP pathway, converting guanosine-5΄-triphoshate (GTP) to cyclic guanosine-3΄,5΄-monophosphate (cGMP) in response to its major physiological stimulant, nitric oxide (NO). Continue reading