Τόμος 28 (2010) – Τεύχος 2 – Άρθρο 11 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 28 (2010) – Issue 2 – Article 11 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

Τίτλος – Title

Αιφνίδιος Καρδιακός Θάνατος και Διατατική Μυοκαρδιοπάθεια

Sudden Cardiac Death and Dilated Cardiomyopathy

Συγγραφέας – Author

Απόστολος Κατσίβας1, Σπύρος Κουρούκλης2

1Καρδιολόγος-Δ/ντής Α’, 2Καρδιολόγος-Σύμβουλος, Καρδιολογική Κλινική Νοσοκομείο Ελληνικού Ερυθρού Σταυρού, Θεσσαλονίκη, Ελλάς

Apostolos Katsivas1, Spyros Kourouklis2

1Cardiologist, Chairman, 2Cardiologist, Consultant, Cardiol Dep, HRCH

Παραπομπή – Citation

Κατσίβας,A., Κουρούκλης,Σ. : Αιφνίδιος Καρδιακός Θάνατος και Διατατική Μυοκαρδιοπάθεια, Επιθεώρηση Κλιν. Φαρμακολ. Φαρμακοκινητ. 28: 165-170 (2010)

Katsivas,A., Kourouklis,S. : Sudden Cardiac Death and Dilated Cardiomyopathy, Epitheorese Klin. Farmakol. Farmakokinet. 28: 165-170 (2010)

Ημερομηνία Δημοσιευσης – Publication Date
1 Δεκεμβρίου 2010 – 2010-12-01
Γλώσσα Πλήρους Κειμένου –
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Ελληνικά – Greek

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Λέξεις κλειδιά – Keywords
Sudden cardiac death, heart failure, ventricular fiblillation, dilated cardiomyopathy, ICD, syncope
Λοιποί Όροι – Other Terms

Στατιστική Μελέτη

Statistical Study

Περίληψη – Summary

The yearly incidence of SCD in the U.S. and Europe is approximated of 0.1-0.2%. Ventricular Tachycardia Fiblillation are the major causes of SCD. B-blockers, ACE inhibitors, ARBS, statins, anticoagulance anantiplatelets drugs reduce mortality. Many studies were conduced to address the efficacy of ICD versus drug therapy in patients with DCM. Syncope has been proved to be associated with poor prognosis in patients with heart failure ICD’s are effective for primary as well as for secondary prevention of SCD.

Αναφορές – References
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4. Bayes de la Luna A., Coumel P., et al.: Ambulatory SCD: Mechanisms of production of fatal arrhythmia on the basis of data from 157 cases. Am. Heart J. 117: 151-159 (1989)

5. Amiodarone Trials Meta-Analysis Investigators: Effect of prophylactic Amiodarone on mortality after AMI and CHF: meta-analysis of individual data from 6500 patients in randomized trials. Lancet 350: 1417-1424 (1997)

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10. Bansch D., Antz M., Boczor S., Volkmer M., Tebbenjohanns J., Seidl K., Block M., Gietzen F., Berger J., Kuck K.H.: Primary prevention of sudden cardiac death in idiopathic dilated cardiomyopathy: The Cardiomyopathy Trial (CAT). Circulation 105: 1453-1458 (2002)

11. Priori S.G., Aliot E., Blomstrom-Lundqvist C., et al.: Update of the guidelines on sudden cardiac death of the European Society of Cardiology. Eur. Heart J. 24: 13-15 (2003)

12. Strickberger S.A., Hummel J.D., Bartlett T.G., Frumin H.I., Schuger C.D., Beau S.L., Bitar C., Morady F.: Amiodarone Versus Implantable Cardioverter-defibrillator: Randomized Trial in Patients with Nonischemic Dilated Cardiomyopathy and Asymptomatic Nonsustained Ventricular Tachycardia-AMIO-VIRT. J. Am. Col. Cardiol. 41: 1707-1712 (2003)

13. Kadish A., Dyer A., Daubert J.P., et al.: Prophylactic defibrillator implantation in patients with nonischemic dilated car-diomyopathy. N. Engl. J. Med. 350: 2151-2158 (2004)

14. Bardy G.H., Lee K.L., Mark D.B., Poole J.E., et al.: Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N. Engl. J. Med. 352: 225-237 (2005)

15. Grimm W., Christ M., Bach J., Muller H.H., Maisch B.: Noninvasive arrhythmia risk stratification in idiopathic dilated cardiomyopathy—Results of the Marburg cardiomyopathy study. Circulation 108: 2883-2891 (2003)

16. Kron J., Hart M., Schual-Berke S., Niles N.R., Hosenpud J.D., McAnulty J.H.: Idiopathic dilated cardiomyopathy. Role of programmed electrical stimulation and Holter monitoring in predicting those at risk of sudden death. Chest 93: 85-90 (1988)

17. Wilber D.J.: Evaluation and treatment of nonsustained ventricular tachycardia. Curr. Opin. Cardiol. 11: 23-31 (1996)

18. ACC/AHA/ESC 2006 guidelines for the management of patients with ventricular arrythmias and the prevention of sudden cardiac death. Europace 8: 746-837 (2006)

19. Brembilla-Perrot B., Donetti J., et al.: Diagnostic value of ventricular stimulation in patients with DCM. Am. Heart J. 121: 1124-1131 (1991)

20. Olshansky B., Poole J.E., et al.: Syncope predicts the out-come of cardiomyopathy patients. Analysis of the SCD-Heft Study. JACC 51: 1277-1282 (2008)

 

 

Online ISSN 1011-6575

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