Τόμος 30 (2016) – Τεύχος 3 – Άρθρο 1 – Review of Clinical Pharmacology and Pharmacokinetics- Διεθνής Έκδοση – Volume 30 (2016) – Issue 3 – Article 1 – Review of Clinical Pharmacology and Pharmacokinetics – International Edition

Title Study in Anti-wrinkle Activity of a Night Cream Containing a Combination of Antioxidants, Phytosteroids and Acetyl-tetrapeptide-9 by Biophysical Methods and Objective Evaluation
Author Athanasia Varvaresou, Spyridon Papageorgiou, Fotini Mellou and Evangelia Protopapa
Affilations Department of Aesthetics and Cosmetology, Faculty of Health and Caring Professions, Technological Educational Institution (TEI) of Athens, Athens, Hellas
Citation Varvaresou A., Papageorgiou S.,  Mellou F., Protopapa E., : Study in Anti-wrinkle Activity of a Night Cream Containing a Combination of Antioxidants, Phytosteroids and Acetyl-tetrapeptide-9 by Biophysical Methods and Objective Evaluation, Review Clin. Pharmakol. Pharmakokinet. Int. Ed. 30(1): 67-70 (2016)
Publication Date Accepted for publication (Final Version): November 28, 2016
Full Text Language English
Keywords Hydrating, firming, anti-wrinkle activity
Other Terms review article
Summary This study presents the association of different active substances in a multifunctional cosmetic formulation. A night cream containing an association of antioxidants (vitamins A, E and resveratrol oligomers), niacinamide, phytosteroids (Soybean sterols and Dioscorea villosa root Extract, rich in diosgenin) and the collagen promoter Acetyl Tetrapeptide-9, was submitted to a clinical efficacy study using biophysical methods. Skin capacitance, suction method and skin microtopography were used for the evaluation of the hydrating, elasticity and anti-wrinkle activity of the formulation after six weeks application. Subjective evaluation of skin texture was also performed. The multifunctional cosmetic formulation studied can be suggested to preventing signs of aging and improving skin texture.
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