Open Access Research
In vitro study of the antibacterial effects of the Cydonia oblonga extract
, Baraa Hamid Hadi3, Lubna Abdul Muttalib Al-Shalah4, Ahmed Saleem Abbas5
*Corresponding author: Nada Khazal Kadhim Hindi, Department of Basic and Medical Sciences, College of Nursing, University of Babylon, Hillah, Iraq, and College of Pharmacy, Al-Mustaqbal University, Hillah, Iraq
Tel.: +964-(0)7725708351
E-mail: nadakhazal@yahoo.com
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Published: 5 May 2024; https://doi.org/10.61873/UAUF7136
Abstract
Cydonia oblonga is effective against many infections and has medicinal properties that are useful in the treatment of many other diseases. The aim of this study was to elucidate the antimicrobial activity (in the form of anti-adherence and anti-biofilm formation) of the aqueous Cydonia oblonga extract. The biological activity of the extract was compared to that of imipenem. All bacterial isolates of Gram-positive and Gram-negative bacteria assessed were found to be susceptible to the Cydonia oblonga extract and the zone of inhibition ranged from 24 to 34 mm. Most bacterial isolates were resistant to the antibiotic, and some bacterial isolates were sensitive to imipenem. The adherence and biofilm formation inhibitory activities in the presence of the aqueous extract of Cydonia oblonga were found to be moderate or elevated in most of the Gram-negative bacteria assessed. According to our findings, the aqueous Cydonia oblonga extract displays great effectiveness (and promise) against many pathogenic bacterial isolates.
Keywords: Cydonia oblonga, antibacterial, biofilm formation, adherence inhibition, in vitro
Please cite as:
Hindi N.K.K, Hadi B.H., Lubna Abdul Muttalib Al-Shalah L.A.M., Abbas A.S. In vitro study of the antibacterial effects of the Cydonia oblonga extract. Rev. Clin. Pharmacol. Pharmacokinet. Int. Ed. 38(Sup2): 117-119 (2024). https://doi.org/10.61873/UAUF7136