Τόμος 1 (1987) – Τεύχος 2 – Άρθρο 1 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 1 (1987) – Issue 2 – Article 1 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

1. Professor of Physiology, University of Athens and Technological Educational Institution (T.E.I) of Athens

2. Editor-in-Chief of Journals “Epitheorese Klinikes Farmakologias και Farmakokinetikes” – Greek Edition and “Review of Clinical Pharmacology and Pharmacokinetics” – International Edition

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2.         A.M. Ristuccia, B.A. Cunha (eds): Antimicrobial Therapy. Raven Press, New York, 1984

3.         Brumfitt, W., Hamilton-Miller,  Principles and practice of antimicrobial chemotherapy. In: Drugs Treatment (T.M. Speight, ed.), 3rd ed., p. 1207, Auckland, 1987

4.         Plessas, Ch.T.: Beta-lactamines: chimie, action, degradation enzymatique et pharmacocingtique. Epitheor. Klin. Farmakol. Farmakokinet. (EH. ekd.) 1: 137 (1983)

5.         D. Greenwood (ed.}: Antimicrobial Chemotherapy. Baillifere Tindalf, London, 1983

6.         P.G. Sammes (ed.): Topics in Antibiotic Chemistry. Vols 1-5, Ellis Horwood, Chichester

7.         Russell. A.D.: Design of antimicrobial chemotherapeutic agents. In: Introduction to Principles of Drug Design (H.J. Smith, H. Williams, eds), p. 241, John Wright, Bristol, 1983

8.         O’Callaghan, C.H.: Structure-activity relationship and β- lactamase resistance. Philos. Trans. R. Soc. London, Ser. B, 289: 197 (1980)

9.         Boyd, D.B., Hermann, R.B., Presti, D.E., Marsh, M.M.: Electronic structures of cephalosporins and penicillins. J. Med. Chem. 18: 408 (1975)

10.       Periti, P.: Co-betalattamine penamiche e cefempenamiche. In: Aggiornamenti di Chemioterapia (G. Gialdroni. Grassi, G. Grassi, eds), p. 170, La Goliardica Pavese, Pavia, 1978

11.       Neu, H.C.: Penicillins. In: Principles and Practice of Infectious Diseases (G.L. Mandell, R.G. Douglas, J.E. Bennett, eds), p. 166, J2nd ed., J. Wiley, New York, 1985

12.       Neu, H.C.: Relation of structural properties of beta-lactam antibiotics and antibacterial activity. Am. J. Med. 79 (Suppl. 2A): 2 (1985)

13.       E.H. Flynn (ed.): Cephalosporins and Penicillins: Chemistry and Biology. Academic Press, New York, 1972

14.       Mandel, G.L: Cephalosporins. In: Principles and Practice of Infectious Diseases (G.L. Mandel, R.G. Douglas, J.E. Bennett, eds), p. 180, 2nd ed., Wiley, New York, 1985

15.       Garzone, P., Lyon, J., Yur V.L.: Third generation and investigational cephalosporins. 1. Structure-activity relationships and pharmacokinetic review. Drug Intell. Clin. Pharm. 17: 507 (1983)

16.       Symposium (Various Authors): Moxalactam international symposium (R.C. Moellering, L.S. Young, eds). Rev. Infect. Dis. 4: S489 (1982)

17.       T.J. Franklin, G.A. Snow (ed.): Biochemistry of Antimicrobial Action. 3rd ed.. Chapman and Hall, London, 1981

18.       Gale, E.F., Cundliffe, E., Reynolds, P.E., Richmond, M.H., Waring, M.J.: The Molecular Basis of Antibiotic Action. 2nd ed., Wiley, London, 1981

19.       Garrod, L.P., Lambert, H.P., O‘Grady, F.: Antibiotic and Chemotherapy. 5th ed., Churchill Livingstone, London, 1981

20.       F.E. Hahn (ed.): Antibiotics. Vol. 5, Part 1: Mechanism of Action of Antibacterial Agents. Springer-Verlag, Stuttgart, 1979

21.       Tipper, D.J., Wright, A.: Structure and biosynthesis of bacterial cell walls. In: The Bacteria (J.R. Sokatch, L A. Ornstein, eds). Vol. 7, p. 291, Academic Press, New York, 1979

22.       Kelley, J.A., Moews, P.C., Know, J.R., Frere, J., Ghuysen, J.: Penicillin target enzyme and the antibiotic binding site. Science 218: 479 (1982)

23.       Spratt, B.G.: Penicillin-binding-proteins and the future of β-lactam antibiotics. J. Gen. Microbiol. 129: 1247 (1983)

24.       Tomasz, A.: Penicillin binding proteins: their role in beta-lactam action and resistance. In: Contemporary Issues in Infectious Diseases. (R. Root, M.A. Sande, eds), Vol. 1, p. 1, Churchill Livingstone, New York, 1984

25.       Tomasz, A.: The mechanism of the irreversible antimicrobial effects of penicillins. Ann. Rev. Microbiol. 33: 131 (1979)

26.       Yocum, R.R., Waxman, D.W., Strominger, J.L.: The mechanism of action of penicillin. J. Biol. Chem. 255: 3977 (1980)

27.       L.F. Bryan (ed.): Antimicrobial Drug Resistance. Academic Press. London, 1984

28- J.M. Hamilton-Smith, J.T. Smith (eds): Beta-lactamases. Academic Press, London, 1979.

29.       Ogawa, H.: Antibiotic resistance in-pathogenic and producing bacteria with special reference to β-lactam antibiotics. Microbiol. Rev. 45: 591 (1981)

30.       Livermore, D.M.: Do β-lactamase ‘trap’ cephalosporins? J. Antimicrob. Chemother. 15: 511 (1985)

31.       Sykes, R.B.: Classification and terminology of enzymes that hydrolyze β-lactam antibiotics. J. Infect. Dig. 145: 762 (1982)

32.       Sykes, R.B., Bush, Κ.: Interaction of new cephalosporins with β-lactamases and β-lactamase-producing gram- negative bacteria. Rev. Infect. Dis. 5 (Suppl. 2): S356 (1983)

33.       Sanders, C.C.: Inducible β-lactamases and non-hydrolytic resistance mechanisms. J. Antimicrob. Chemother, 13: 1 (1984)

34.       Jaffe, A., Chabbert, Y.A., Semonin, 0.: Role of porin proteins OmpF and OmpC in the permeation of beta- lactams. Antimicrob. Agents Chemother. 22: 942 (1982)

35- Kobayashi, Y., Takahashi, T., Nakae, T.: Diffusion of beta-lactam antibiotics through liposomes membranes containing purified porins. Antimicrob. Agents Chemother. 22: 775 (1982)

36.       Noble, J.T., Barza, M.: Pharmacokinetic properties of the newer cephalosporins. A valid basis for drug selection? Drugs 30: 175 (1985)

37.       Rehm, S.J., McHenry, M.C.: Oral antimicrobial drugs. Med. Clin. North Am. 67: 57 (1983)

38.       Norris, S.M.: Cephalosporin antibiotic agents. II. First and second-generation agents. Infect. Control 5: 57 (1984)

39.       Fried, J.S., Hinthorn, D.R.: Cephalosporins. DM31: 1 (July) 1985

40.       Plessas, Ch.T., Plessas, S.T.: Influence de la nourriture sur la biodisponibiliti des medicaments. Epitheor. Klin. Farmakol. Farmakokinet. {EH. ekd.J 1: 15 (1983)

41.       Barza, M., Weinstein, L.: Pharmacokinetics of the penicillins in man. Clin. Pharmacokin. I: 297 (1976)

42.       Welling, P.G.: Interactions affecting drug absorption. Clin. Pharmacokin. 9: 404 (1984)

43.       Ginsburg, C.M.: Comparative pharmacokinetics of cefadroxil, cefaclor, cephalexin and cephradine in infants and children. J. Antimicrob. Chemother. 10 (Suppl. B); 27 (1982)

44.       Quintiliani, R. et al.: Cephalosporins: Overview. In: Antimicrobial Therapy (A.M. Ristuccia, B.A. Cunha, eds), p. 289, Raven Press, New York, 1984

45.       Tartaglione, T.A., Polk, R.E.: Review of new second-generation cephalosporins: Cefonicid, ceforanide and cefuroxime. Drug Intell. Clin. Pharm. 19: 188 (1985)

46.       Balant, L. et al.: Clinical pharmacokinetics of third generation cephalosporins. Clin. Pharmacokinet. 10: 101 (1985)

47.       Craig, W.A., Welling, P.G.: Protein binding of antimicrobials: clinical pharmacokinetic and therapeutic implications. Clin. Pharmacokinet. 2: 252 (1977)

A.        PENICILLINS

1.         Brogden, R.N. et al.: Amoxycillin: Review of its antibacterial and pharmacokinetic properties and therapeutic use. Drugs 9: 88 (1975)

2.         Drusano, G.L. et al.: Acylampicillins: Mezlocillin, piperacillin and azlocillin. Rev. Infect. Dis. 6: 13 (1984)

3.         Eliopoulos, G.M., Moellering, R.C. Jr.: Azlocillin, mezlocillin and piperacillin: New broad-spectrum penicillins. Ann. Intern. Med. 97: 755 (1982)

4.         Ehrnebo, M., Nilsson, S.-O., Boreus, L.O.: Pharmacokine-tics of ampicillin and its prodrugs, bacampicillin and pivampicillin, in man. J. Pharmacokinet. Biopharm. 7: 429 (1979)

5.         Holmes, B, et al.: Piperacillin: A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 28: 375 (1984)

6.         Humbert, G.r Thauvin, C., Lecomte, F.: Acquisitions recentes en antibiotherapie. Mid, et Hyg. 43: 666 (1985)

7.         McCloskey, R.V. et al.: Microbiology, pharmacology and clinical use, of mezlocillin sodium. Pharmacotherapy 2: 300 (1982)

8.         McCracken, G.H. Jr.: Comparative evaluation of amino-penicillins for oral use. Pediatr. Infect. Dis. 2: 317 (1983)

9.         Molavi, A., LeFrock, JX.: Antistaphylococcal penicillins. In: Antimicrobial Therapy (A.M. Ristuccia, B.A. Cunha, eds), p. 183, Raven Press, New York, 1984

10.       Neu, H.C.: Antistaphylococcal penicillins. Med. Clin. North Am. 66: 51 (1982)

11.       Neu, H.C.: Carbenicillin and ticarcillin. Med. Clin. North Am. 66: 61 (1982)

12.       Neu, H.C.: Amdinocillin: Novel penicillin: Antimicrobial activity, pharmacology and clinical use. Pharmacotherapy 5: 1 (1985)

13.       Pary, M.F., Pancoast, S.J.: Antipseudomonal penicillins. In: Antimicrobial Therapy (A.M. Ristuccia, B.A. Cunha, eds), p. 197, Raven Press, New York, 1984

14.       Scheife, R.T., Neu, H.C.: Bacampicillin hydrochloride: Chemistry, pharmacology and clinical use. Pharmacotherapy 2: 313 (1982)

15.       Wright, A.J., Wilkowske, C.J.: Penicillins. Mayo Clin. Proc. 58: 21 (1983)

B.        CEPHALOSPORINS

16.       Barriere, S.L, Mills, J.: Ceforanide: Antibacterial activity, pharmacology and clinical efficacy. Pharmacotherapy 2: 322 (1982)’

17.       Carmine, A.A. et al.: Cefotaxime: Review of its antimicrobial activity, pharmacological properties and therapeutic use. Drugs 25: 223 (1983)

18.       Carmine, A.A. et al.: Moxalactam (Latamoxef): A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 26: 279 (1983)

19.       Dudley, B/I.N. et al.: Review of cefonicid, long-acting cephalosporin, din. Pharm. 3: 23 (1984)

20.       Eichenwald, H.F.: Antimicrobial therapy in infants and children: Update 1976-1985. Part I. J. Pediatr. 107: 161 (1985)

21.       Funk, E.A., Strausbaugh, L.J.: Antimicrobial activity,, pharmacokinetics, adverse reactions, and therapeutic indications of cefoperazone. Pharmacotherapy 2: 185 (1982)

22.       Gold, B„ Rodriguez, W.J.: Cefuroxime: Mechanisms of action, antimicrobial activity, pharmacokinetics, clinical applications, adverse reactions and therapeutic indications. Pharmacotherapy 3: 82 (1983)

23.       B.L. Hoffbrand, M. Kory (eds): Cephalexin: Twelve years of clinical and laboratory experience. Postgrad. Med. J. 59 (Suppl. 5): 1 (1983)

24.       R.N. Jones, et al. (eds): Workshop on five years of clinical experience with cefotaxime (with special references to gram-positive infections). Infection 13 (Suppl. 1): Si (32 papers) (1985)

25.       J.O. Klein, H.C. Neu (eds): Empiric therapy of bacterial infections. Evaluation of cefoperazone. Rev, Infect. Dis. 5 (Suppl. 1): S1 (22 papers) (1983)

26.       H.P. Lampert, et al. (eds): Ceftazidime in clinical practi¬ce. J. Antimicrob. Chemother 12 (Suppl A): 1 (63 papers) (1983)

27.       R.C. Moellering, Jr (ed.): Ceftriaxone: Long-acting cepha-losporin. Am. J. Med. 77 (Suppl. 4C): 1 (21 papers) (1984)

28.       H.C. Neu, I. Phillips (eds): Cefotaxime. J. Antimicrob. Chemother. 14 (Suppl. B): 1 (50 papers) (1984)

29.       H.C. Neu (ed.): Advances in cephalosporin therapy: Be-yond the third generation. Am. J. Med. 79 (Suppl. 2A): 1 (19 papers) (1985)

30.       H.C. Neu, M. Turck, I. Phillips (eds): Ceftizoxime, broad-spectmm β-lactamase stable cephalosporin. J. Antimicrob. Chemother. 10 (Suppl. C): 1 (46 papers) (1982)

31.       I. Phillips, R. Wise (eds): Role of cefadroxil in oral antibiotic therapy. J. Antimicrob. Chemother. 10 (Suppl. B): 1 (24 papers) (1982)

32.       I. Phillips, R. Wise, D.A. Leigh (eds): Cefotetan: New cephamycin. J. Antimicrob. Chemother. 11 (Suppl. A): 1 (32 papers) (1983)

33.       Rehm, S.J., McHenry, M.C.: Oral antimicrobial drugs. Med. Clin. North Am. 67: 57 (1983)

34.       Richards, D.M., Brogden, R.N.: Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 29: 105 (1985)

35.       Richards, D.M., Heel, R.C.: Ceftizoxime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs, 29: 281 (1985)

36.       Richards, D.M. et al.: Ceftriaxone. A review of its anti-bacterial activity, pharmacokinetic properties and therapeutic use. Drugs 27: 469 (1984)

37.       Sahm, D.F. et al.: β-Lactam antibiotics: Third-generation cephalosporins and other newer lactams. Antimicrob. News let t. 2: 33 (1985)

38.       Sanders, C.V. et al.: Cefamandole and cefoxitin. Ann. Intern. Med. 103: 70 (1985)

39.       Smith, B.R.: Cefsulodin and ceftazidime, two antipseudomonal cephalosporins. Clin. Pharm. 3: 373 (1984)

40.       Stamm, J.M.: Cefmenoxime: In vitro activity. Am. J. Med. 77 (Suppt. 6A): 1 (1984)

41.       Ward, A., Richards, D.M.: Cefotetan: Review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 30: 382 (1985)

42.       Yost, R.L., Ramphal, R.: Ceftazidine review. Drug Intell. Clin. Pharm. 19: 509 (1985)

C.        OTHER β-LACTAMINS

43.       Barza, M.: Imipenem: First of new class of beta-lactam antibiotics. Ann. Intern. Med. 103: 552 (1985)

44.       Birnbaum, J. et al.: Carbapenems, new clas of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin. Am. J. Med. 78 (Suppl. 6A): 3 (1985)

45.       Brogden, R.N., Heel, R.C.: Aztreonam: A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use. Drugs 31: 96 (1986)

46.       A.M. Geddes, W. Stille (eds): Imipenem: First threnamycin anbitiotic. Rev. Infect. Dis. 7 (Suppl. 3): S353 (24 papers) (1985)

47.       Giamarellou, H. et al.: Evaluation of aztreonam in difficult-to-treat infections with prolonged postreatment follow-up. Antimicrob. Agents Chemother. 26: 245 (1984)

48.       Guay, D.R.P., Koskoletos, C.: Aztreonam, new monobactam antimicrobial. Clin. Pharm. 4: 516 (1985)

49.       Jackson, D. et al.: Augmentin: Absorption, excretion and pharmacokinetic studies in man. Postgrad. Med. Sp. Rep. (Sept.-Oct.): 51 (1984)

50.       J.S. Remington (ed.): Carbapenems: New class of antibiotics. Am. J. Med. 78 (Suppl. 6A): 1 (25 papers) (1985)

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