Τόμος 2 (1988) – Τεύχος 2 – Άρθρο 3 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής – Διεθνής Έκδοση – Volume 2 (1988) – Issue 2 – Article 3 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Formation of acetamido-homo-aza-steroids and bis homo-aza-steroids by Beckmann rearrangement
Author Panayotis Catsoulacos

Laboratory of Pharmaceutical Chemistry, University of Patras, Greece

Citation Catsoulacos, P. : Formation of acetamido-homo-aza-steroids and bis homo-aza-steroids by Beckmann rearrangement, Epitheorese Klin. Farmakol. Farmakokinet. 2(2): 91-102 (1988)
Publication Date 1988-10
Full Text Language English
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Keywords Beckmann, rearrangement, steroidal oximes, formation, bis homo-aza-steroids, acetamido-homo-aza-steroids, carboxylic, leukemia, solid tumors.
Other Terms review article
Summary In this review article the Beckmann rearrangement of steroidal oximes and the formation of bis homo-aza-steroids and acetamido-homo-aza-steroids are reported. It is concluded that steroidal lactam is required for activity of homo-aza-steroidal esters of carboxylic derivatives of N,N-bis (2-chloroethyl) aniline in leukemias and solid tumors.
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Relative Papers Structure-antileukemic activity relationships of modified steroidal alkylating agents in P388 and L1210 murine leukemias

Panayotis Catsoulacos

Online ISSN 1011-6575

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