Volume 42 (2024) – Supplementary Issue 1 – Article 2 – Epitheorese Klinikes Farmakologias kai Farmakokinetikes

Abstract
Background: One of the most common and potentially fatal pathogens is resistant Staphylococcus aureus. When choosing an effective medication for the management of staphylococcal infections, knowledge of the regional isolates’ pattern of antimicrobial sensitivity is fundamental. Aim: Our study aimed at identifying the antibiotic susceptibility patterns of S. aureus based on samples collected at an Iraqi teaching hospital. Methodology: S. aureus isolates from various clinical cases presented at the Al-Ramadi Teaching Hospital were identified by using standard microbiological methods. Antimicrobial susceptibility tests through the use of the Kirby-Bauer disc diffusion tests and minimum inhibitory concentrations were also undertaken on an automated VITEK 2 Compact system (bioMérieux). Results: A total of 20 antimicrobial agents were used in this study, while a total of 100 S. aureus samples have been collected from various clinical cases. These samples were isolated in most cases from wounds (37.5%) and skin swabs (25%). As far as the patterns of antimicrobial resistance are concerned, S. aureus was found to be susceptible to gentamicin (68%), tetracycline (80%), rifampicin (85%), erythromycin (68%), ciprofloxacin (85%), and imipenem (90%). A total of 86% of the S. aureusisolates were found to be methicillin-resistant, while 35% of the isolates were identified as being trimethoprim-resistant. Moreover, 100% of the S. aureus isolates were found to be resistant to benzylpenicillin, and only 3% of the isolates were identified as resistant to vancomycin. Conclusion: The knowledge of the antibiotic susceptibility patterns of the S. aureus isolates from the various clinical cases presented at Al-Ramadi Teaching Hospital will prove useful in their targeted treatment with antibiotics.