Τόμος 3 (1989) – Τεύχος 1 – Άρθρο 4 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 3 (1989) – Issue 1 – Article 4 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Steroidal alkylating agents in cancer chemotherapy
Author Panayotis Catsoulacos

Laboratory of Pharmaceutical Chemistry, University of Patras, Greece, and Nuclear Research Center “Demokritos”, Aghia Paraskevi Attikis, Greece

Citation Catsoulacos, P.: Steroidal alkylating agents in cancer chemotherapy, Epitheorese Klin. Farmakol. Farmakokinet. 3(1): 46-59 (1989)
Publication Date 1989-07
Full Text Language English
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Keywords Steroidal alkylating agents, steroid molecule, leukemia, cancer, chemotherapy.
Other Terms review article
Summary We report the chemical combination of steroid with alkylating agent. This combination can be divided into two groups, depending on the forming bond between the alkylating congener and the steroid molecule. For activity it is necessary an easily cleaved ester bond. Most steroidal alkylating agents have been inactive in L1210 and P388 leukemias.
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Relative Papers Structure-antileukemic activity relationships of modified steroidal alkylating agents in P388 and L1210 murine leukemias
Panayotis Catsoulacos

Online ISSN 1011-6575

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