Title | Αspects de la synthèse et de l ‘utilisation des premiers isostères 3′ et 5′ azotés de l’ AMP cyclique | |
Author | Guido Zosimo-Landolfo
Faculté de Pharmacie de l’Université Libanaise, Dékouané, Liban |
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Citation | Zosimo-Landolfo, G.: Αspects de la synthèse et de i ‘utilisation des premiers isostères 3′ et 5′ azotés de l’ AMP cyclique, Epitheorese Klin. Farmakol. Farmakokinet. 5(3): 119-123 (1991) | |
Publication Date | Received for publication: 10 October 1991
Accepted for publication: 15 October 1991 |
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Full Text Language | English – French | |
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Keywords | Phosphoramides, thiophosphoramides, AMP cyclique, analogues de nucleosides. | |
Other Terms | review article | |
Summary | In this paper we review the preparation and the usefulness of the first Cyclic Adenosine Monophosphate analogs, bearing an intracyclic nitrogen. | |
References | 1. Jastorff, B., Hettler, H.: Phosphorylation of B’-amino- 5′-deoxynucleosides. Tetrahedron Lett. 30: 2543 (1969)
2. Jastorff. B., Hettler, H.: Nucleotid-analoge von 5′-Amino-5′-desoxy-nucleosiden. Chem. Ber. 102: 4119 (1969) 3. Murayama, A., Jastorff, B., Hettler, H.: Synthesis of 5′-amido analogs of adenosine (3′-5)-cyclophosphates. Angew. Chem. Internat. Edit. 9: 640 (1970) 4. Murayama, A., Jastorff, B., Cramer, F., Hettler, H.: 5′-amido analogs of adenosine 3′,5′-cyclic. monophosphate. J. Org. Chem. 36: 3029 (1971) 5. Murayama, A., Jastorff, B., Hettler, H., Cramer, F.: Die Stereoselektivität bei der Synthese von 5′-N-substituierten 5′-Amido-Analoga des Adenosin-3′, 5′-cyclophosphat-p-nitro-phenylesters. Chem. Ber. 106: 3127 (1973) 6. Jastorff, B., Krebs, T.: Analoge des Adenosin-(3′,5′)- cyclophosphats mit Stickstoff und Schwefelatomen im Phosphatring. Chem. Ber. 105: 3192 (1972) 7. Morr, M., Kula, M.-R., Roesler, G., Jastorff, B.: Synthesis of 3′-amido-3′-deoxyadenosine 3′,5′-cyclophos- phate. Angew. Chem. Internat. Edit 13: 280 (1974) 8. Morr, M., Kula, M.-R., Ernst, L.: Synthesis and 13C NMR spectra of 3′-amido analogs of adenosine 3′,5′- cyclic monophosphate. Tetrahedron 31: 1619 (1975) 9. Morr, M., Menge), R.: Synthese der Cycloamide der xylo-3′-Amino-3′-desoxyadenosin-5′-phosphorsaure und 5′-thionophosphorsäure, sweier neuer cAMP-Analoga. Chem. Ber. 110: 3947 (1977) 10. Morr, M., Ernst, L.: Zur Reaktion von Aminonucleo- siden mit Thiophosphorylierungsreagenzien. Chem. Ber. 111: 2152 (1978) 11. Morr, M.: Synthese des 5′-thio-3′-Amido-5′.3′-dideso- xyadenosin-3,5′-cyclophosphats, ein cAMP-derivat mit S und N im cyclophosphatring. Tetrahedron Lett. 2127 (1976) 12. Simon, L., Shuman, D., Robins, R.: The chemistry and biological properties of nucleotides related to nucleoside 3′,5′-cyclic phosphates. Adv. Cyclic Nucleotide Res. 3: 225 (1973) 13. Jastorff, B„ Bar, H.-P.: Effects of 5’-amido analogues of adenosine 3′:5′ monophosphate and adenosine 3′:5’-monophosphothioate on protein, kinase, binding protein and phosphodiesterases. Eur. J. Biochem. 37: 497 (1973) 14. Panitz, N., Rieke, E., Morr, M., Wagner, K., Roesler, G., Jastorff, B.: The 3′-amido and 5′-amido analogues of adenosine 3′:5′-monophosphate; interaction with cAMP-specific proteins. Eur. J. Biochem. 55: 415 (1975) 15. Jastorff, B„ Hoppe, J., Morr, M.: A model for the chemical interactions of adenosine 3′:5′.-monophosphate with the R subunit of protein kinase type I. Eur. J. Biochem. 101: 555 (1979) 16. Malchow, D., Fuchila, J., Jastorff, B.: Correlation of substrate specificity of cAMP phosphodiesterase in dictyostetium discoideum with chemostatic activity of cAMP-analogues, FEBS Lett. 34: 5 (1973) 17. Mato, J., Konijn, T.: The chemostatic activity of cyclic AMP and AMP derivatives with substitutions in the phosphate moiety in dictyostelium discoideum. FEBS Lett. 75: 173 (1977) 18. Mato, J., Jastorff, B., Morr, M., Konijn, T.; A model for cyclic AMP chemoreceptor interaction in dictyostelium discoideum. Biochim. Biophys. Acta 544: 309 (1978) |
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