| Title | Combinatorial synthesis in medicinal chemistry: implications in drug discovery and development | |
| Authors | Julian Smith1 and Tony Cooper2
1. Department of Chemistry, University of Exeter, Stocker Road, Exeter, Devon, U.K., EX4 4QD 2. Receptor Research Limited, Wainhouse Comer, Bude, Cornwall; U.K. EX23 OAR |
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| Citation | Smith, J., Cooper, T.: Combinatorial synthesis in medicinal chemistry: implications in drug discovery and development, Epitheorese Klin. Farmakol. Farmakokinet. 11(2-3): 104-107 (1997) | |
| Publication Date | 1997 | |
| Full Text Language | English | |
| Order – Buy | pharmakonpress[at]pharmakonpress[.]gr | |
| Keywords | Combinatorial chemistry, drugs. | |
| Other Terms | review article | |
| Summary | Combinatorial chemistry is having a major impact on the design and implementation of drug discovery programmes throughout the pharmaceutical and agrochemical industries. Rapid advances have already been made in the variety of chemical transformations now practicable on the solid phase. Combinatorial chemistry is a powerful tool that has radically altered the way in which large numbers of diverse compounds can be produced. The development of this technique and its implications in drug discovery are discussed. | |
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