Τόμος 13 (1999) – Τεύχος 1 – Άρθρο 4 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 13 (1999) – Issue 1 – Article 4 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Effect of c-amp on the intraocular pressure of the human and rabbit eye
Authors Stelios Hatzigakis², Charis Carageorgiou¹, Ilias Migdalis¹, Andreas Petounis¹ and Dionysios D. Varonos²

1. Pharmacology Department, Medical School, Athens University, Athens, Greece

2. Ophthalmology Department, NIMTS Military Hospital, Athens, Greece

Citation Hatzigakis, S., Carageorgiou, C., Migdalis, I., Petounis, A., Varonos, D.D.: Effect of c-amp on the intraocular pressure of the human and rabbit eye, Epitheorese Klin. Farmakol. Farmakokinet. 13(1): 37-42 (1999)
Publication Date Accepted for publication: 15 June 1999
Full Text Language English
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Keywords c-AMP, intraocular pressure, rabbit eye, human eye.
Other Terms review article
Summary The effect of c-AMP on the intraocular pressure of rabbit and human eye was investigated. The c-AMP was administered i.v. and subconjunctivally in the posterior chamber of the rabbit and by instillation on the human eye. A reduction of the intraocular pressure was observed in both cases, more pronounced after the posterior chamber administration in relation to the subconjunctival or the intravenous one. The reduction of the I.O.P. in the human eye was actually small (2 mgHg) although statistically significant (p<0.01).
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