| Title | Non-toxic goitre in Greece before and after the correction of iodine deficiency | |
| Author | Demetrios A. Koutras
Athens University Endocrine Unit, Evgenidion Hospital, Athens, Greece |
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| Citation | Koutras, D.A.: Non-toxic goitre in Greece before and after the correction of iodine deficiency, Epitheorese Klin. Farmakol. Farmakokinet. 14(1): 25-27 (2000) | |
| Publication Date | Received for publication: 6 December 1999
Accepted for publication: 10 December 1999 |
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| Full Text Language | English | |
| Order – Buy | Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €)
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| Keywords | Non-toxic goitre, iodine deficiency, Greece. | |
| Other Terms | review article | |
| Summary | A generation ago, iodine-deficiency was prevalent in our country, and most of the goitres diagnosed had all the characteristics of iodine deficiency. Now iodine deficiency has been virtually eliminated, thanks to iodized salt and to silent iodine prophylaxis. Now, about two thirds of the goitres diagnosed are associated with autoimmunity, probably induced by the higher iodine intake. In both the past iodine-deficient time and the present iodine-sufficient era, the iodine intake is not strikingly different between goitrous and nongoitrous persons. So, we think, that other (? genetic or ‘host’) factors modify the effects of the iodine intake. | |
| References | 1. HADJIDAKIS S.G., KOUTRAS D.A., & DAIKOS G.K.: Endemic goitre in Greece: family studies. J. Med. Gen. 1: 82-87 (1964)
2. MALAMOS B., KOUTRAS D.A., KOSTAMIS P., KRALIOS A.C., RIGOPOULOS G., ZEREFOS N.: Endemic goiter in Greece: epidemiologic and genetic studies. J. Clin. Endocrinol. Metab. 29: 688-695 (1966) 3. MALAMOS B., MIRAS K., KOUTRAS D.A., KOSTAMIS P., BlNOPOULOS D., MANTZOS J., LEVIS G., RIGOPOULOS G., ZEREFOS N., TASSOPOULOS C.N.: Endemic goiter in Greece: metabolic studies. J. Clin. Endocrinol. Metab. 29: 696-704 (1966) 4. MALAMOS B., KOUTRAS D.A., MARKETOS S.G., RIGOPOULOS G.A., YATAGANAS X.A., BINOPOULOS D., SFONTOURIS J., PHARMAKIOTIS A.D., VOUGHT R.L, LONDON W.T.: Endemic goiter in Greece: an iodine balance study in the field. J. Clin. Endocrinol. Metab. 27: 1372-1380 (1967) 5. KOUTRAS D.A., PAPAPETROU P.D., YATAGANAS X., MALAMOS B.: Dietary sources of iodine in areas with and without iodine-deficiency goiter. Am. J. Clin. Nutr. 23: 870- 874 (1970) 6. MALAMOS B., KOUTRAS D.A., RIGOPOULOS G.A., PAPAPETROU P.D., GOUGAS E., KELPERI H., MORAITOPOULOS C., DAVJ E., LEONARDOPOULOS J.: Endemic goiter in Greece: some new epidemiologic studies. J. Clin. Endocrinol. Metab. 32: 130-139 (1971) 7. MALAMOS B., KOUTRAS D.A., KOSTAMIS P., RIGOPOULOS G.A., ZEREFOS N.S., YATAGANAS X.A.: Endemic goiter in Greece: a study of 379 twin pairs. J. Med. Gen. 4: 16-18 (1967) 8. KOUTRAS D.A., SOUVATZOGLOU A., PANDOS P.G., PAPACHRISTOU D.N., PlPERINGOS G.D., SFONTOURIS J.: Iodide organification defect in iodine deficiency endemic goiter. J. Clin. Endocrinol. Metab., 47: 610-614 (1978) 9. KOUTRAS D.A., KATSOUYANNI E.K., LIVADAS D.P., PIPERINGOS G.D., TZONOU A., TRICHOPOULOS D.: An epidemiologic survey of thyroid enlargement among schoolchildren in a non-endemic area. Endokrinologie 79: 349-354 (1982) 10 Koutras D.A., Piperingos G., Mantzds J., Boukis M., Karaiskos K.S., Hadjiioannou S.: Iodine nutrition and iodine deficiency disorders in Greece: signs and improvement. In: iodine Deficiency in Europe (Deiange F. et al., eds), Pp. 421-426, Plenum Press, New York, 1993 11 DOUFAS A.G., MASTORAKOS G., HAJIIOANNOU S., TSELENI-BALAFOUTA S., PIPERINGOS G., BOUKIS M.A., MANTZOS E., KARAISKOS K.S., MANTZOS J., ALEVIZAKI M., KOUTRAS D.A.: Autoimmune goiter is the predominant form of nontoxic goiter in Greece after iodine deficiency correction. To be published (1998) |
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Online ISSN 1011-6575
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