| Title | Morpheaform basal cell carcinoma of the skin: a difficult to treat type of basal cell carcinoma histopathological study of 759 cases and review of the literature | |
| Authors | Fragiski A. Anthouli-Anagnostopoulou¹, Evagelos Kanelos¹, Eftichia Hatziolou² and Sotiris Anagnostopoulos²
1. Faculty of Health and Caring Professions, Technological Educational Institution (TEI), Athens, Greece 2. Histopathological Laboratory, Andreas Sygros Hospital, Athens, Greece 3. TEKOR Informatics S.A., Athens, Greece |
|
| Citation | Anthouli-Anagnostopoulou, A.A., Kanelos, E., Hatziolou, E., Anagnostopoulos, S.: Morpheaform basal cell carcinoma of the skin: a difficult to treat type of basal cell carcinoma histopathological study of 759 cases and review of the literature, Epitheorese Klin. Farmakol. Farmakokinet. 15(1): 43-49 (2001) | |
| Publication Date | Received for publication: 5 November 2000
Accepted for publication: 10 December 2000 |
|
| Full Text Language | English | |
| Order – Buy | Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €)
pharmakonpress[at]pharmakonpress[.]gr |
|
| Keywords | Basal cell carcinoma of the skin (BCC), morphea-like basal cell carcinoma of the skin (MBCC), sclerosing type basal cell carcinoma of the skin, aggressive basal cell carcinoma of the skin, immune response, desmoplastic basal cell carcinoma of the skin, therapy modalities. | |
| Other Terms | review article | |
| Summary | The purpose of this study was to recognize from 2972 basal cell carcinomas (BCCs) of the skin those BCCs that showed histologically: a) infiltrative growth pattern, b) fibrosclerosing activity of the underlying stroma and c) absence of inflammatory lymphoid reaction (immune response). A retrospective study of 759 biopsies of sclerosing type BCC was performed through last six years according to: a) sex, b) age, c) location single or multifocal and d) the presence or not of immune response in the histological picture. Sclerosing BCCs lesions are observed almost equal in both sexes with slight predominance to men (1.12/1) 60-80 years old (55.5%), affect mainly nose and cheeks areas (53.8%) and show little (20.7%) or no inflammatory reaction (43%) in the histologic picture. 13.3% of BCCs had a multifocal location. Mohs micrographie surgery was the preferable applied therapy. Morpheaform sclerosing BCC, unlike other BCCs types, is a special type of BCC that presents an aggressive behavior with possibility of recurrences or metastases, similar to squamous cell carcinoma (SCC), as a consequence of the absence of lymphoid inflammatory reaction and the presence of multifocal location. | |
| References | 1. Sexton M., Jones D.B., Maloney M.E.: Histologic pattern analysis of basal cell carcinoma, Study of a series of 1039 consecutive neoplasms. J. Am. Acad Dermatol. 23: 1118-1126 (1990)
2. Cohen H.J.: Morphea-like basal cell epithelioma. Inter. J. Dermatol. 28: 684 (1989) 3. Crocker H.R.: Case reports. Br. J. Dermatol. 7: 89 (1895) 4. Me Cormack C.J., Kelly J.W., Dorevitch A.P.: Differences in age and body distribution of the histological subtypes of basal cell carcinoma. A possible indicator of differing causes. Arch. Dermatol. 138: 593-596 (1997) 5. Betti R., inselvini E., Carducci M., Crosti C.: Age and site prevalence of histologic subtypes of basal cell carcinomas. Int. J. Dermatol. 43: 174-176 (1995) 6. Richman T., Penneys N.S.: Analysis of morpheaform basal cell carcinoma. J. Cutan. Pathol. 15: 359-362 (1988) 7. Barsky D., Vasileff W.J.: Extensive Morphea form basal cell carcinoma invasion of the iris and the orbital contents. Med. J. Henry Ford Hospital 35: 71-73 (1987) 8. Menard P., Bertrand J.C., Goudal J.Y.: Pre-auricular sclerodermiform basocellular carcinoma extending to the temporomandibular joint. Presentation of a case. Rev. Stomatol. Et Chir. Maxillofaciale 92: 22-26 (1991) 9. Niparko J.K., Swanson N.A., Baker S.R., Telian S.A., Sullivan M.J., Kermick J.L.: Local control of auricular, periauricular, and external canal cutaneous malignancies with Mohs surgery. Laryngoscope 108: 1047-1051 (1990) 10. Gussack C.S., Schlitt M., Lushington A., Woods K.E.: Invasive basal cell carcinoma of the temporal bone. J. Ear, Nose and Throat. 68: 605-606, 609-611 (1989) 11. Karagas M.R.: Occurrence of cutaneous basal cell and squamous cell malignancies among those with a prior history of skin cancer. The Skin Cancer Prevention Study Group, J. Invest. Dermatol. 102: 105-135 (1994) 12. Moy R.L., Moy L.S., Matsuoka L.Y., Bennett R.G., Uitto J.: Selectively enhanced procollagen gene expression in sclerosing (morphea-like) basal cell carcinoma as reflected by elevated pro alpha 1(1) and pro alpha 1(111) procollagen messenger RNA steady-state levels. J. Invest. Dermatol. 92: 634-638 (1988) 13. Ernst T.M., Mueller-Mai C.: Immunophenotyping and morphometry of infiltrates in variants of basalioma. Z Hautkr. (Ger.) 62: 1143, 1137-1140, 1143-1144 (1987) 14. Deng, J.S., Brod B.A., Saito R., Tharp M.D.: Immune- associated cells in basal cell carcinomas of the skin. J. Cutan. Pathol. 22: 140-146 (1996) 15. Leffell D.J., Headington J.T., Wong D.S., Swanson N.A.: Aggressive-growth basal cell carcinoma in young adults. Arch. Dermatol. 127: 1663-1667 (1991) 16. Brown C.I., Perry A.E.: Incidence of perineural invasion in histologically aggressive types of basal cell carcinoma. Am. J. Dermatopathol. 22: 123-125 (2000) 17. Soufir N., Basset-Seguin N.: Skin carcinogenesis. Rev. Prat. (Fre.) 49: 813-817 (1999) 18. Emmett A.J.: Surgical analysis and biological behavior of 2277 basal cell carcinomas. Aust. N. Z. J. 68: 855-863 (1990) 19. Friedman H.I., Williams T., Zamora S., al-Assaad Z.A.: Recurrent basal cell carcinoma in margin-positive tumors. Ann. Plast. Surg. 38: 232-235 (1997) 20. Dämmert К., Kallioinen M.: Desmoplastic trichoepithelioma. Clinical aspects, histology and differential diagnosis. Hautarzt. (Ger.) 38: 603-606 (1987) 21. Ко C.B., Walton S., Keczkes K.: Extensive and fatal basal cell carcinoma: a report of three cases. Br. J. Dermatol. 127: 164-167(1992) 22. Snow S.N., Saht W., Lo J.S., Mohs F.E., Warner T., Dekkinga J.A., et al.: Metastatic Basal cell carcinoma: Report of five cases. Cancer 79: 328-335 (1994) 23. Brega Massone P.P., Lequaglie C., Ferro F., Gallino G., Conti B., Cataldo I.: Pulmonary metastasis of basal cell carcinoma of the skin. 3 cases reports. Chin Ital. (Ital.) 52: 165-169 (2000) 24. Silverman M.K., Kopf A.W., Grin C.M., Bart R.S., Levenstein M.J.: Recurrence rates of treated basal cell carcinomas. Part 2: Curettage-Electrodesiccation. J. Der-matol. Surg. Oncol. 17: 720-726 (1991) 25. Germann G., Bernstein-Sommer В., Petrovici V., Steinau H.U.: Differential oncologically adequate therapy of basalioma. Handchir. Mikrochir. Plastic. Chin 24: 151- 158(1992) 26. Breuninger H., Schippert W., Black B., Rassner G.: The margin of safety and depth of excision in surgical treatment of basalioma. Use of 3-dimensional histologic study of 2.016 tumors. Hautarzt. (Ger.) 48: 693-700 (1989) 27. Hacker S.M., Browder J.F., Ramos-Caro F.A.: Basal cell carcinoma. Choosing the best method of treatment for a particular lesion. Postgrad. Med. 93: 101-104, 106-108, 111 (1993) 28. Jaramillo-Ayerbe F.: Cryosurgery in difficult to treat basal cell carcinoma. Int. J. Dermatol. 39: 223-229 (2000) 29. Lawrence C.M.: Mohs surgery of basal cell carcinoma. A critical view. Bn J. Plast. Surg. 48: 599-606 (1993) 30. van Baardwijk A.A., Verhaegh M.E., Krekels G.A., Vermeuien A.H., Neuman H.A.: Mohs’ method of micro-graphic surgery as treatment for recurrent basal cell carcinoma. Ned. Tijdschr. Geneeskd (Den.) 141: 524-529 (1997) |
|
| Relative Papers |
Online ISSN 1011-6575
Άρθρα Δημοσιευμένα σε αυτό το Περιοδικό Καταχωρούνται στα:
- Chemical Abstracts
- Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
Συντακτικη Επιτροπή-Editorial Board
| ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 2001 – ANNUAL SUBSCRIPTION 2001 | |
| Γλώσσα Πλήρους Κειμένου – Full Text Language | Αγγλικά – English |
| Παραγγελία – Αγορά – Order – Buy | Ηλεκτρονική Μορφή: pdf (70 €) – Digital Type: pdf (70 €)
pharmakonpress[at]pharmakonpress[.]gr |
| Έντυπη Μορφή (70 € + έξοδα αποστολής) – Printed Type (70 € + shipping)
pharmakonpress[at]pharmakonpress[.]gr |
|