Τόμος 15 (2001) – Τεύχος 3 – Άρθρο 13 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 15 (2001) – Issue 3 – Article 13 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title In vitro studies of cell proliferation and cell death for the evaluation of natural products and synthetic compounds
Authors Harris Pratsinis1,2, Anastasia Konstantinidou¹, Augoustina Liaouri¹, Dimitris Kletsas² and Panagiotis Davaris²

1.       Department of Pathology, Medical School, University of Athens, 75 Mikras Asias str., 115 27 Athens, Greece

2.    Laboratory of Cell Proliferation & Ageing, Institute of Biology, N.C.S.R. Demokritos, 153 10 Athens, Greece

Citation Pratsinis, H., Konstantinidou, A., Liaouri, A., Kletsas, D., Davaris, P.: In vitro studies of cell proliferation and cell death for the evaluation of natural products and synthetic compounds, Epitheorese Klin. Farmakol. Farmakokinet. 15(3): 163-168  (2001)
Publication Date Accepted for publication: 1 August 2001
Full Text Language English
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Keywords Cell culture, cell proliferation, cell death, apoptosis.
Other Terms review article
Summary In vitro testing is of primary importance for the preliminary screening of the effects of drugs, cosmetics, food additives and many other kinds of substances. This review presents briefly the most common in vitro methods for the study of cell proliferation and cell death as tools for the evaluation of natural products and synthetic compounds. Advantages and disadvantages of these methods, as well as some hints for the set-up of such in vitro assay systems are also here presented.
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