| Title | Is basic research, going purely for the scientific truth, outdated today: reflections on some critical questions reinforced by the 50th anniversary of discovery of the chemical structure of DNA | |
| Author | Erich Hecker
Heidelberg, Germany |
|
| Citation | Hecker, E.: Is basic research, going purely for the scientific truth, outdated today: reflections on some critical questions reinforced by the 50th anniversary of discovery of the chemical structure of DNA, Epitheorese Klin. Farmakol. Farmakokinet. 18(2): 195-201 (2004) | |
| Publication Date | Accepted for publication: 2004 | |
| Full Text Language | English | |
| Order – Buy | Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €)
pharmakonpress[at]pharmakonpress[.]gr |
|
| Keywords | – | |
| Other Terms | review article | |
| Summary | Mankind’s approaches to understand its world by scientific research originated in late Renaissance and initiated the Scientific Revolution. Scientific understanding of nature is suggestive of utilizing novel knowledge to improve mankind’s life: Applied Research. Novel scientific knowledge-problems by its intrinsic Janus-headed nature in utilizing scientific results by mankind. The Janus-headed nature and/or increasing expenses in the acquisition of novel scientific knowledge may demand for certain controls by scientific community and/or by human society. In mankind’s Research for Survival basic research going purely for the scientific truth remains the condition sine qua non. | |
| References | 1. Hecker E., Bulenandt A.: Bombykol revisited – Reflections on a pioneering period and some of its consequences. In: Techniques in Pheromone Research (H.E. Hummel et.al., eds). Pp. 1-44, Springer, New York, 1984
2. Karison P., Liicher M.: Pheromone. Ein Nomenklatur-vorschlag für eine Wirkstolfldasse. Naturwissenschaften 46: 63-64 (1959) 3. Hecker E.: Historical essay on the general scientific and of an organized national approach to the fight against cancer. In: 100 years of organized cancer research – 100 Jahre organisierter Krebsforschung (U. Eckarl, A.W. Bauer, eds). Pp. 5-10, Georg Thieme Verlag, Stuttgart, 2000 4. Hecker E., Rippmann F.: Outline of a descriptive general theory of environmental chemical cancerogenesis – experimental thereshol doses for tumor promoters mechanisms of environmental mutagenesis/carcinogenesis. In: Mechanisms of environmental mutagenesis-carcinogenesis (A. Kappas, ed.). Pp. 167-173, Plenum Press, New York, 1990 5. Krauter G., von der Lieth C.W., Schmidt R., Hecker E.: Structure/activity relationships of polyfunctional diterpenes of the tigliane type. A pharmacophore model for protein-kinase-C activators based on structure/activity studies and molecular modeling of the tumor promoters 12-O-tetradecanoylphorbol 13- acetate and 3-O-tetradecanoylingenol. Eur. J. Biochem. 242: 417-427 (1996) 6. Hecker E.: Tumorpromotoren (Konditionalkanzerogene) – eine neuartige Kategorie von Krebsrisikofakloren und ihre aktuelle Bedeutung in der Umwelt des Menschen. Deutsche Akademie der Naturforscher, Leopoldina, Halle, Jahrbuch 1997 (R3) Bd. 41, p. 195-219 (1998) 7. Hecker E., Schlesinger M.: Cancer Research: Worldwide challenge for Biomedicine, ln: Cancer Research and Cooperation. German-lsraeli Cooperation in Cancer Research. The first 20 Years (S. Glasmacher, Y. Degani, E. Hecker, eds) Heidelberg: Deutsches- Krebsfonschungszentmm, Jerusalem: State of Israel, Ministry of Science, p. 88-98,1999 8. Butenandt A., Weidel W., Becker E.: Kynurenin als Augenpigmentsbildung auslosendes Agens bei Insekten. Naturwissenschaften 28: 63; and 447 (1940) 9. Beadle G.W., Tatum EL: Genetic Control of Biochemical Reactions in Neunospora. Proc. Natl. Acad. Sci. U.SA. 22: 499-506 (1941) 10. Delbrück M.: Bacterial Viruses (Bacteriophages). Adv. Enzymol 2: 1-32 (1942) 11. Aveiy O.T., McLeod C.M., McCarthy M.: Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus Type III. J. Exptl. Med. 79: 137-158 (1944) 12. Cairns J.: Last days in Arcadia – Millenium essay. Nature 401: 19 (1999) 13. Jaenisch R., Wilmut J.: Don’t clone humans! Science 291: 2552 (2001) |
|
| Relative Papers |
Online ISSN 1011-6575
Άρθρα Δημοσιευμένα σε αυτό το Περιοδικό Καταχωρούνται στα:
- Chemical Abstracts
- Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
Συντακτικη Επιτροπή-Editorial Board
| ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 2004 – ANNUAL SUBSCRIPTION 2004 | |
| Γλώσσα Πλήρους Κειμένου – Full Text Language | Αγγλικά – English |
| Παραγγελία – Αγορά – Order – Buy | Ηλεκτρονική Μορφή: pdf (70 €) – Digital Type: pdf (70 €)
pharmakonpress[at]pharmakonpress[.]gr |
| Έντυπη Μορφή (70 € + έξοδα αποστολής) – Printed Type (70 € + shipping)
pharmakonpress[at]pharmakonpress[.]gr |
|