Τόμος 18 (2004) – Τεύχος 2 – Άρθρο 13 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 18 (2004) – Issue 2 – Article 13 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Department of Pathophysiology, School of Medicine, University of Athens, Greece

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2.    Scofield R.H., Farris A.D., Horsfall A.C., Harley J.B.: Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins. Arthritis Rheum. 42: 199-209 (1999)

3.    Wahren-Herlenius M. Muller S., Isenberg D.: Analysis of B- cell epitopes of the Ro/SS-A autoantigen. Immunol. Today 20: 234-240 (1999)

4.    Moutsopoulos N.M., Routsias J.G., Vlachoyiannopoulos P.G., Tzioufas A.G., Moutsopoulos H.M.: B-Cell Epitopes of Intracellular Autoantigens: Myth and Reality. Mol. Medicine 6: 141-151 (2000)

5.    Tzioufas A.G., Tzortzakis N.G., Panou-Pomonis E., et al.: The clinical relevance of antibodies to ribosomal-P common epitope in two targeted systemic lupus erythematosus populations: a large cohort of consecutive patients and patients with active central nervous system disease. Ann. Rheum. Dis.: 99-104 (2000)

6.    Yiannaki E.E., Tzioufas A.G., BAchmann M., et al.: The value of synthetic linear epitope analogues of La/SSB for the detection of autoantibodies to La/SSB; specificity, sensitivity and comparison of methods. Clin. Exp. Immunol. 112: 152-158 (1998)

7.    Petrovas C.J., Vlachoyiannopoulos P.G., Tzioufas A.G., et al.: A major Sm epitope enchored to sequential oligopeptide carriers is a suitable antigenic substrate to detect anti-Sm antibodies, J. Immunol. Methods 220: 59-68 (1998)

8.    Tzioufas A.G., Wassmuth R., Dafni U.G., et al.: Clinical, Immunologic and Immunogenetic aspects of autoantibody production against Ro/SSA, La/SSB and their linear epitopes in primary Sjogren’s Syndrome (pSS): a European multicenter study. Ann. Rheum. Dis. 61: 398-404 (2002)

9.    McCluskey J., Farris A.D., Keech C.L., et al.: Determinant spreading: lessons from animal models and human disease. Immunol. Rev. 164: 209-229 (1998)

10.  Fatenejad S., Mamula M.J., Craft J.: Role of intermolecular/intrastructural B- and T-cell determinants in the diversification of autoantibodies to ribonucleoprotein particles. Proc. Natl. Acad. Sci. U.S.A. 90: 12010-12014 (1993)

11.  Reynolds P., Gordon T.P., Purcell A.W., Jackson D.C., McCluskey J.: Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice. J. Exp. Med. 184: 1857-1870 (1996)

12.  Yiannaki E., Vlachoyiannopoulos P.G., Manoussakis M.N., et al.: Study of antibody and T-cell responses in rabbits immunized with synthetic human B cell epitope analogues of La (SSB) autoantigen. Clin. Exp. Immunol. 121: 1-7 (2000)

13.  Bost K.L., Blalock J.E.: Preparation and use of complementary peptides. Methods Enzymol. 163: 16-28 (1989)

14.  Blalock J.E.: Genetic origins of protein shape and inter-action rules. Nat. Med. 1: 876-878 (1995)

15.  Villain M., Jackson P.L., Manion M.K., et al.: De novo design of peptides targeted to the EF hands of calmodulin. J. Biol. Chem. 275: 2676-2685 (2000)

16.  Routsias J.G., Touloupi E., Dotsika E., et al.: Unmasking the anti-La/SSB response in sera from patients with Sjogren’s Syndrome by specific blocking of anti-idiotypic antibodies to La/SSB antigenic determinants. Mol. Med. 8: 293-336 (2002)

17.  Van den Eydde B.J.G.B., Probst-Kepper M., Michaux L., et al.: A new antigen recognized by cytosolic T lymphocytes on a human kidney tumor results from reverse strand transcription. J. Exp. Med. 190: 1793-1799 (2000)

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