Τόμος 18 (2004) – Τεύχος 3 – Άρθρο 2 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 18 (2004) – Issue 3 – Article 2 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Oxidative stress, photoaging and topical antioxidant protection
Authors Athanasia Varvaresou, Efthimios Tsirivas, Eleana Tsaoula and Evangelia Protopapa

Department of Aesthetics and Cosmetology, School of Health and Caring Professions, Technological Educational Institution, Egaleo, Athens, Greece

Citation Varvaresou, A., Tsirivas, E., Tsaoula, E., Protopapa, E.: Oxidative stress, photoaging and topical antioxidant protection, Epitheorese Klin. Farmakol. Farmakokinet. 18(3): 261-266 (2004)
Publication Date Received for publication: 10 August 2004

Accepted for publication: 15 September 2004

Full Text Language English
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Keywords Photodamage, photoaging, topical antioxidants in cosmetology, vitamin C, vitamin E, ubiquinone, superoxide dismutase, peroxidase rich fennel seed extract (Foeniculum vulgare), selenium, silymarin, soy isoflavones, green tea polyphenols, melatonin and CM-glucan.
Other Terms review article
Summary New methods to protect skin from photodamage and reactive oxygen species (ROS) generation are necessary, since sunscreens do not provide full spectral protection against UV light Additionally, sunscreen ingredients may become ROS themselves, when activated by UV irradiation, and sunscreen chemicals may be absorbed into skin to potentially cause harm. Therefore, apart from using sunscreens to diminish the intensity of UV radiation reaching, the development of novel strategies to prevent ROS from reacting with biomolecules is a further valuable approach in limiting UV-induced skin damage. This presentation briefly reviews the most common topical antioxidants used in cosmetology. Vitamin C, vitamin E, ubiquinone, superoxide dismutase, peroxidase rich fennel seed extract (Foeniculum vulgare), selenium, silymarin, soy isoflavones, green tea polyphenols, melatonin and CM-glucan are the topical antioxidants included in this review.
References 1.    Kefala V., Protopapa E., Plessas S.T.: Photoaging: an esthetic problem: Prevention or treatment? Rev. Clin. Pharmacol. Pharmacokinet. Int. Ed. 15: 33-42 (2001)

2.    Berneburg M., Piettenberg H., Krutmann J.: Photoaging of human skin. Photodermatol. Photoimmunoi. Photomed. 16: 239-244 (2000)

3.    Young A.R., Potten C.S., Nikaido O., Parsons P.G., Boenders J., Ramsden J. M., et al: Human melanocytes and keratinocytes exposed to UVB or UVA in vivo show comparable levels of thymine dimers. J. Invest. Dermatol. 111: 936-940 (1998)

4.    Ziegler A., Jonason A.S., Leffell D.J., Simon J.A., Sharma H.W., Kimmwlman J., et al: Sunburn and p53 in the onset of skin cancer. Nature 372: 773-776 (1994)

5.    Noonan      F.P., De Fabo E.C.: Immunosuppression by ultraviolet B radiation: initiation by urocanic acid. Immunol Today 13: 250-254 (1992)

G.    Hanson K.M., Simon J.D.: Epidermal trans urocanic acid and the UVA induced photoaging of the skin. Proc. NatL Acad. Sci USA 95: 10576-10578 (1998)

7.    Stadtman E.R.: Protein oxidation and aging. Science 257: 1220-1224(1992)

8.    Gaboriau F., Demoulins-Giacco N., Tirache I., Morliere P.: Involvement of singlet oxygen in ultraviolet A-induced lipid peroxidation in cultured human fibroblasts. Arch. Dermatol. Res. 287: 338-340 (1995)

9.    Trautinger F.: Mechanisms of photodamage of the skin and its functional consequences for skin aging. Clin. Exp. Derm. 26: 573-577 (2001)

10.  Knowland J., McKenzie E.A., McHugh P.J., Gridland N.A.: Sunlight-induced mutagenicity of a common sun-screen ingredient. FEBS Lett. 336: 184-185 (1993)

11.  Thiele J.J., Dreher F., Packer L.: Antioxidant defense systems in skins. In: (Eisner P., Maibach H.I., editors) Cosmoceuticals: Drugs vs Cosmetics. Pp. 145-187, Marcel Dekker, New York, 2000

12.  Levine M., Wang Y.H., Padaytty S.J., Morrow J.: A new recommended dietary allowance of vitamin C for healthy young women. Proc. Natl. Acad. Sci. USA 98: 9842-9846 (2001)

13.  Pinnell S.R., Yang H. S.t Omar M., Riviere N.M., De Buys H.V., Walker L.C., et al.: Topical L-ascorbic acid: percutaneous absorption studies. Dermatol. Surg. 27: 137-142 (2001)

14.  Darr D., Combs S., Dunston S., Manning T., Pinnell S.: Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage. Br. J. Dermatol. 127: 247-253 (1992)

15.  Darr D., Dunston S., Pinnell S.: Effectiveness of anti-oxidants (vitamin C and E) with and without sunscreens as topical photoprotectants. Acta Derm. Venereot. 76: 264- 268 (1996)

16.  Nayama S., Takehana M., Kanke M., Itoh S., Ogata E.( Kobayashi S.: Protective effects of sodium-L-ascorbyl-2-phosphate on the development of UVB-induced damage in cultured mouse skin. Biol. Pharm. Bull. 22: 1301-1305 (1999)

17.  Geecin J.C., Gordon J.S., Berg R.A.: Regulation of collagen synthesis in human dermal fibroblasts by the sodium and magnesium salts of ascorbyl-2-phosphate. Skin Pharmacol. 6: 65-71 (1993)

18.  Azzi A., Breyer I., Feher M., Pastori M., Riccrarelli R., Spycher S., et al.: Specific cellular responses to alphatocopherol. J. Nutr. 130: 1649-1652 (2000)

19.  Thomas C.E., McLean L.R., Parker R.A., Phlweiler D.F.: Ascorbate and phenofic antioxidant interactions in prevention of liposomal oxidation. Lipids 27: 543-550 (1992)

20.  Roshchupkin D.I., Pistsov M. Yu, Potapenko A. Ya.: Inhibition of ultraviolet light-induced erythema by antioxidants. Arch. Dermatol. Res. 266: 91-94 (1979)

21.  Bisset D.I., Chatterjee R., Hannon D.P.: Photoprotective effect of superoxide-scavenging antioxidants against ultraviolet radiation induced chronic skin damage in the hairless mouse. Photodermatol. Photoimmunol. Photomed. 7: 56-62 (1990)

22.  Gensler H.L., Magdaleno M.: Topical vitamin E inhibition of immunosuppression and tumorigenesis induced by UV irradiation. Nutr. Cancer 15: 97-110 (1991)

23.  Alberts D.S., Godman R., Xu M.U., Dorr R.T., Quinn J., Welch K., et al: Disposition and metabolism of topically administered alphatocopherol acetate: a common ingredient of commercially available sunscreens and cosmetics. Nutr. Cancer 26: 193-201 (1996)

24.  Jurkiewicz B.A., Bissett D.L., Buettner F.: Effect of topically applied tocopherol on ultraviolet radiation-mediated free radical damage in skin. J. Invest. Dermatol. 104: 484-488(1995)

25.  Shindo Y., Itt E., Han D., et al.: Dose-response effects of acute ultraviolet irradiation on antioxidants and molecular markers of oxidation in murine epidermis and dermis. J. Invest. Dermatol. 102: 470-475 (1995)

26.  Stoyanovsky D.A., Osipov A.N., Quina P.J., et al.: Ubiquinone dependent recycling of vitamin E radicals by superoxide. Arch. Biochem. Biophys. 323: 343-351 (1995)

27.  Hoppe U., Bergemann J., Dimbeck W., et al: Coenzyme Q10 a cutaneous antioxidant and energizer. Biofactors 9: 371-378 (1999)

28.  Halliwell B., Gutteridge J.M.C.: Free radicals in Biology and Medicine. Pp 36-109, 2nd Ed, Oxford University Press, Oxford, 1998

29.  Lods L.M., Dres C., Johson C., Scholz D.B., Brooks G. J.: The future of enzymes in cosmetics. Int. J. Cosm. Sci. 22: 85-94 (2000)

30.  Allan C.B., Lacourciere G.M., Stadtman T.C.: Responsiveness of selenoproteins to dietary selenium. Annu. Rev. Nutr. 13: 1-16 (1999)

31.  Burke K.E, Clive J., Combs G.F.,Jr, Commisso J., Keen C.L., Nakamura R.M.: Effects of topical and oral vitamin E on pigmentation and skin cancer induced by ultraviolet irradiation in Skh2: hairless mice. Nutr. Cancer 38: 87-97 (2000)

32.  Chaterjee M.L., Katiyar S.K., Mohan R.R., Agarwal R.: A flavonoid antioxidant drug (silymarin) affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model. Cancer Res. 59: 622-632 (1999)

33.  Boulet M.J., Oddens B.J., Lehert P., Vermer H.M., Visser A.: Climacteric and menopause in seven south-east Asian countries. Maturitas 19: 157-176 (1994)

34.  Bingham S.A., Atkinson C., Liggins J., Bluck L., Coward A.: Phytoestrogens-where are we now? Br. J. Nutr. 79: 393-406 (1998)

35.  Greenwell P., Hu W., Kohanski R.A., Ramirez F.: Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta-1 stimulation of alpha-2 (I) collagen gene expression Mol. Cell Biol. 15: 6813-6819 (1995)

36.  Hwang J., Sevanian A., Hodis, H.N., Ursini, F.: Synergistic inhibition of LDL oxidation by phytoestrogens and ascorbic acid. Free Radic. Biol. Med. 29: 79-89 (1998)

37.  Wiseman H., O’ Reilly J.D., Adlercreutz H., Mallet A.L., Bowey E.A., et al: Isoflavone phytoestrogens consumed in soy decrease F-2-isoprostane concentrations and Increase resistance of low-density lipoprotein to oxidation in human. Am. J. Clin. Nutr. 72: 395-400 (2000)

38.  Shyong E.Q., Lu Y.H., Lazinsky A., Saladi R.N., Phelps R.G., Austin L.M., et al: Effects of isoflavone 4′,5,7- trihydroxy isoflavone (genistein) on psoralen plus ultraviolet A radiation-induced photodamage. Carcinogenesis 23: 317-321 (2002)

39.  Rice-Evans C.: Implications of the mechanisms of action of tea polyphenols as antioxidants in vitro for chemo- prevention in humans. Proc. Soc. Exp. Biol. Med. 220: 262-266 (1999)

40.  Elmets C.A., Singh D., Tubesing K., Matsui M., Katiyar S., Mukhtar H.: Cutaneous photoprotection from ultraviolet injury by green tea polyphenols. J. Am. Acad. Dermatol. 44: 425-432 (2001)

41.  Reiter R.J., Tang L., Garcia J.J., et al: Pharmacological action of melatonin in oxygen radical pathophysiology. Life Sci. 60: 2255-2271 (1997)

42.  Gulcin I., Buykokuroglu M. E., Oktay M., Kufrevioglu O.I.: On the in vitro antioxidative properties of melatonin. J. Pineal. Res. 33: 167-171 (2002)

43.  Iakovou K., Varvaresou A., Kourounakis A.P., Stead K.t Sugden D., Tsotinis A.: Design, synthesis and biological evaluation of novel conformationally restrained melatoninergic analogs. J. Pharm. Pharmacol. 54: 147-156 (2002)

44.  Reiter R.J., Tann D.X, Osuna C., et al: Actions of melatonin in the reduction of oxidative stress. J. Biomed. Sci. 7: 444-458 (2000)

45.  Saija A., Tomaino A., Trombetta D., Pellegrino M., Tita B., Caruso A., Casteli F.: Interaction of melatonin with model membranes and possible implications in its photo- protective activity E. J. Pharm. Biopharm. 53: 209-215 (2002)

46.  Bangha E., Eisner P., Kistler G.S.: Supression of UV-induced erythema by topical treatment with melatonin (N- acetyl-5-methoxytryptamine). A dose response study. Arch. Dermatol. Res. 288: 522-526 (1996)

47.  Dreher F., Gabard B.t. Schwindt D.A, Maibach H.: Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythema: a human study in vivo. Br. J. Dermatol. 139: 332-339 (1998)

48.  Zülli F., Suter F., Biltz H., Nissen H. P.: Improving skin function with CM-glucan, a biological response modifier from yeast. Int. J. Cosm. Set. 20: 79-86 (1998)

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