Τόμος 20 (2006) – Τεύχος 1 – Άρθρο 1 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 20 (2006) – Issue 1 – Article 1 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title DNA microarray techniques review
Authors Stavros Glentis¹, Ian Craft², Alan Thornhill² and  Joyce C. Harper¹

1. Department of Obstetrics and Gynaecology, University College London, 86-96 Chenies Mews, London WC1E 6HX, UK

2. London Fertility Centre, Cozens House, 112a Harley Street, London W1G 7JH, UK

Citation Glentis, S., Craft, I., Thornhill, A., Harper, J.C.: DNA microarray techniques review, Epitheorese Klin. Farmakol. Farmakokinet. 20(1): 5-11 (2006)
Publication Date Accepted for publication (Final version): 15 April 2006
Full Text Language English
Order – Buy  Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €) 

pharmakonpress[at]pharmakonpress[.]gr

Keywords Microarray, CGH-arrays, molecular biology, biotechnology, genetic diagnosis.
Other Terms review article
Summary DNA microarray technology has the ability to determine and analyze thousands of genes simultaneously. This has led to microarrays being one of the most powerful tools in molecular biology which can be used in most areas of biology and medicine. Routine tests will be the next step for microarrays including prenatal and preimplantation genetic diagnosis, forensic sciences and pharmacogenomics. However, designing a microarray experiment is not easy. Different technologies and experimental approaches have been used from different companies concerning probes, platforms, fabrication, labelling, scanning and data analysis each with advantages and disadvantages. For accurate results, a designing experiment has to consider all these different methods and decide which approach would give robust results.
References 1. Choudhuri S.: Microarrays in Biology and Medicine. J. Biochem. Mol. Toxicol. 18: 171-179 (2004)

2. Sevent N., Cussenot O.: DNA microarrays in clinical practice: past, present and future. Clin. Exp. Med. 3: 1-3 (2003)

3. Hertwig F., Nuber U.A.: DNA microarrays: ten years old but not old hat. In: DNA Microarrays. Pp. 1-6, Chapter 1, Taylor and Francis Group Publishing, 2005

4. Neinloth A.N., Boorman G.A., Paules R.S.: cDNA microarray analysis and its role in toxicology – a case study. In: DNA Microarrays. Pp. 7-24, Chapter 2, Taylor and Francis Group Publishing, 2005

5. Sultmann H., Bunev A., Ruschhaupt M., Huber W., Juner R., Gunawan B., Fuzesi L., Pouska A.: Identification of gene expression patterns for a molecular diagnosis of kidney tumors. In: DNA Microarrays. Pp. 39-50, Chapter 4, Taylor and Francis Group Publishing, 2005

6. Veltmann J., Vissers L.: Molecular Karyotyping by means of array CGH: Linking gene dosage alterations to disease phenotypes. In: DNA Microarrays. Pp. 139-156, Chapter 11, Taylor and Francis Group Publishing, 2005

7. Fiegler H., Gribble SM., Carter N.: DNA microarrays: Analysis of Chromosomes and their aberrations. In: DNA Microarrays. Pp. 157-170, Chapter 12, Taylor and Francis Group Publishing, 2005)

8. Gouroundi K., Lykeridou K.: Risk in public health. Rev. Clin. Pharmacol. Pharmacokinet. 19: 93-98 (2005)

9. Gouroundi K., Lykeridou K.: Screening in public health: case of antenatal screening for Down’s syndrome. Rev.   Clin. Pharmacol. Pharmacokinet. 19: 117-126 (2005)

10. Ekins R., Chu F.: Microarrays: Their origins and applications. Trends Biothechnol. 17: 217-218 (1999)

11. Hardiman G.: Microarray platforms-Comparisons and contrasts. Pharmacogenomics 5: 487-502 (2004)

12. Southern E., Mir K., Shchepinov M.: Molecular interactions on microarrays. Nat. Genet. 21 (Suppl.): 5-9 (1999)

13. Shchepinov M., Case-Green S., Southern E.: Steric factors influencing hybridisation of nucleic acids to oligonucleotide arrays. Nucleic Acids Res. 25: 1155-1161 (1997)

14. LeProust E., Zhang Yu P., Zhou X., Gao X.: Characterization of oligodeoxyribonucleotide synthesis on glass plates. Nucleic Acids Res. 29: 2171- 2180 (2001)

15. Gillespie D., Spiegelman S.: A quantitative assay for DNA-RNA hybrids with DNA immobilised on a membrane. J. Mol. Biol. 12: 829-842 (1965)

16. Khrapko K.R., Lysov Yu.P., Khorlyn A.A., Shick V.V., Florentiev V.L., Mirzabekov A.D.: An oligonucleotide hybridisation approach to DNA sequencing. FEBS lett. 256: 118-122 (1989)

17. Livshits M., Mirzabekov A.: Theoretical analysis of the kinetics of DNA hybridisation with gel-immobilised oligonucleotides. Biophys. J. 71: 2795-2801 (1996)

18. Cheung V., Morley M., Aguilar F., Massimi A., Kucherlapati R., Childs G.: Making and Reading microarrays. Nat. Genet. 21 (suppl.): 15-19 (1999)

19. Duggan D., Bittner M., Chen Y., Meltzer P., Trent J.: Expression profiling using cDNA microarrays. Nat. Genet. 21 (suppl.): 10-14 (1999)

20. Schena M., Shalon D., Heller R., Chai A., Brown P.O., Davis R.W.: Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. Proc. Natl. Acad. Sci. USA 93: 10614-10619 (1996)

21. Cai W., Mao J., Chow C., Damani S., Balmain A., Bradley A.: Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays. Nat. Bio-thech 20: 393-396 (2002)

22. Lipshutz R., Fodor S., Gingeras T., Lockhart D.: High density synthetic oligonucleotide arrays. Nat. Genet. 21 (suppl.): 20-24 (1999)

23. McGall G.: The efficiency of light-directed synthesis of DNA arrays on glass substrates. J. Am. Chem. Soc. 119: 5081-5090 (1997)

24. Pirrung M., Fallon L., MgGall G.: Proofing of photolithographic DNA synthesis with 3’5’-dimethoxybenzoinyloxycarbonyl-protected deoxynucleosides phophoramidites. J. Organic Chem. 63: 241-246 (1998)

25. Baum M., Bielau S., Rittner N., Schmid K., Eggelbusch K., Dahms M., Schlauersbach A., Tahedl H., Beier M., Guimil R., Scheffler M., Hermann C., Funk J.M., Wixmerten A., Rebscher H., Honig M., Andreae C., Buchner D., Moschel E., Glathe A., Jager E., Thom M., Greil A., Bestvater F., Obermeier F., Burgmaier J., Thome K., Weichert S., Hein S., Binnewies T., Foitzik V., Muller M., Stahler C.F., Stahler P.F.: Validation of a novel, fully integrated and flexible microarray benchtop facility for gene expression profiling. Nucleic acid Res. 31(23): E151 (2003)

26. Bowtell D.: Options available – from start to finish- for obtaining expression data by microarray. Nat. Genet. 21 (suppl.): (25-32) (1999)

27. Fodor S.P., Read J.L., Pirrung M.C., Stryer L., Lu A.T., Solas D.: Light-directed, spatially addressable parallel chemical synthesis. Science 251: 767-773 (1991)

28. Fodor S.P., Rava R.P., Huang X.C., Pease A.C., Holmes C.P., Adams C.L.: Multiplexed biochemical assays with biological chips. Nature 364: 555-556 (1993)

Relative Papers

Online ISSN 1011-6575

Άρθρα Δημοσιευμένα σε αυτό το Περιοδικό Καταχωρούνται στα:

Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor

Τι είναι η Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση-Οδηγίες προς τους Συγγραφείς – 
What is Epitheorese Klinikes Farmakologias 
και Farmakokinetikes-International Edition-Instrunctions to Authors

Άρθρα Δημοσιευμένα στην Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – 
Articles Published in Epitheorese Klinikes Farmakologias 
και Farmakokinetikes-International Edition

Συντακτικη Επιτροπή-Editorial Board

ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 2006 – ANNUAL SUBSCRIPTION 2006
Γλώσσα Πλήρους Κειμένου – Full Text Language Αγγλικά – English
Παραγγελία – Αγορά – Order – Buy Ηλεκτρονική Μορφή: pdf (70 €) – Digital Type: pdf (70 €)

pharmakonpress[at]pharmakonpress[.]gr

Έντυπη Μορφή (70 € + έξοδα αποστολής) – Printed Type (70 € + shipping)

pharmakonpress[at]pharmakonpress[.]gr

 

 

 

Bookmark the permalink.

Comments are closed.