| Title | Acne or acnes: is acne vulgaris an auto immune disease? | |
| Authors | Ioanna Grek and Anthony M. Kyriakopoulos
Department of Aesthetics and Cosmetology, School for Professions of Health and Welfare, Technological Education Institution of Athens, Athens, Greece |
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| Citation | Grek, I., Kyriakopoulos, A.M.: Acne or acnes: is acne vulgaris an auto immune disease?, Epitheorese Klin. Farmakol. Farmakokinet. 21(1): 55-57 (2007) | |
| Publication Date | Accepted for publication (Final version): 15 January 2007 | |
| Full Text Language | English | |
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| Keywords | Acne, acne vulgaris, auto inflammatory syndromes. | |
| Other Terms | review article | |
| Summary | Acne vulgaris pathogenesis is attributed to many factors. The man etiological factor remains to be identified. Recently research on the cellular and cytokine profile of a new type of autoimmune diseases named as autoinflammatory syndromes showed common findings with acne vulgaris. Complementary, genetic studies on the gene expression of autoimmune diseases showed resemblance with acne. The combination of an autoimmune response on a susceptible genetic background may explain in the future some of the plethora of presentations seen in acne vulgaris patients. | |
| References | 1. Shalita M.R.: Clinical aspects of acne. Dermatology 196: 93-94 (1987)
2. Zouboulis Ch.C., Eady A., Philpott M., Goldsmith L.A., Orfanos C.E., Gunliffe W.C., Rosenfield R.: What is the pathogenesis of acne? Exp. Dermatol. 14: 143-152 (2005) 3. Zouboulis Ch.C.: Human skin: an independent peripheral endocrine organ. Hom. Res. 54: 230-242 (2000) 4. Zouboulis Ch.C.: The human skin as a hormone target and an endocrine gland. Hormones 3: 9-26 (2004) 5. Chen W., Thiboutot D., Zouboulis Ch.C.: Cutaneous androgen metabolism – basic research and clinical perspectives. Invest Dermatol. 119: 992-1007 (2002) 6. Frisch M., Orfanos C.E., Zouboulis Ch.C.: Sebocytes are the key regulators of androgen homeostasis in human skin. >. Invest. Dermatol. 116: 793-800 (2001) 7. Skurkovich B., Skurkovich S.: Inhibition of IFN- gamma as a method of treatment of various autoimmune diseases, including autoimmune diseases. Ernst Schering Res. Found. Workshop 56: 1-27 (2006) 8. Brydges S., Kaster D.L.: The systemic autoinflammatory diseases: Inborn errors of the innate immune system. Curr. Top. Microbiol. Immunol. 305: 127-160 (2006) 9. Webster G.F., Leyden J.J., Tsai C.-C., Baehni P., McArthur W.P.: Polymorphonuclear leukocyte lysosomal enzyme release in response to Propionibacterium acnes in vitro and its enhancement by sera from patients with inflammatory acne. J. Invest. Dermatol. 74: 398-401 (1980) 10. Webster G.F., Indrisano S.P., Leyden J.J.: Antibody titers to Propionibacterium acnes cell wall carbohydrate in nodulocystic acne patients. J. Invest. Dermatol. 84: 496¬500 (1985) 11. Webster G.F., Leyden J.J., Norman M.P.: Complement activation in acne vulgaris: Consumption of complement by comedones. Infect. Immun. 26: 186-188 (1979) 12. Kuby J.: Cytokines in Immunology. Pp. 248-249, Freeman W.H., 1992 13. Sedgwick J.B., Bergstresser P.R., Hurd E.R.: In-creased superoxide generation by normal granulocytes incubated in sera from patients with psoriasis. J. Invest. Dermatol. 176: 158-163 (1981) 14. Markinkiewcz J., Biedron R., Biolecka A., Kaspowcz A., Mak M., Tarkosz M.: Susceptibility of Propiobacterium acnes and Staphylococcus epidermidis to killing by MPO- halide system products. Implications for tauramine bromamine as a new candidate for topical therapy in treating acne vulgaris. Arch. Immunol. Ther. Exp. (Warz) 54: 61-68 (2006) 15. Eichenfield A.H.: Minocycline and Autoimmunity. Curr. Opm. Pediatr. 11: 447-456 (1999) 16. Paraskevaidis A., Drakoulis N., Roots I., Orfanos C.E., Zouboulis Ch.C.: Polymorphisms in the Human Cyto¬chrome P-450 1A1 Gene (CYP1A1) as a factor for developing acne. Dermatology 196: 171-175 (1998) |
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| Relative Papers |
Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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