Τόμος 21 (2007) – Τεύχος 1 – Άρθρο 12 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 21 (2007) – Issue 1 – Article 12 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Tumor markers or cancer markers
Author Konstantinos Tsochas, M.D., P.D.

Technological Educational Institution (T.E.I.) of Athens, Athens, Greece

Citation Tsochas, K.: Tumor markers or cancer markers, Epitheorese Klin. Farmakol. Farmakokinet. 21(1): 83-90 (2007)
Publication Date Accepted for publication (Final version): 15 January 2007
Full Text Language English
Order – Buy  Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €) 

pharmakonpress[at]pharmakonpress[.]gr

Keywords Cancer, tumors, markers.
Other Terms review article
Summary In the present publication is attempted a general classification of all using cancer indicators in functional tables, in order to they help the at day medical action. We believe that, their daily use with the crossed from each other parameters, many times over constitutes real puzzle in the clinical diagnostics that is also in-creased with the various paces of laboratorial results. Thus, in Table 1 are included all ln use cancer markers with their values (physiologic, modified and high), with their choices (main and secondary) regarding their report in malignant situations, but also their appearance in benign diseases, for contradistinction and their essential exploitation. In Table 2 is reported the symbols and the complete nomenclature for each one of cancer markers, while the Table 3 is reported in the man and secondary cancer markers, for the more basics localizations of cancer Finally, Table 4 it separately records the proposed cancer markers for preventive control (check up), in man and female as additional for smokers. As an introduction, are included a historical retrospection and characterization those who were recorded as monoclonal antibodies and their specialization, in combination polyclonal that is also in use, without certain the safety monoclonal in serious situations, as the various localizations of the cancer.
References –      Abbate X., Correale. M., Musci M: Monoclonal antibody B 27.29 against mucinous breast cancer associated antigen CA 27.29 in breast cancer. Br. Cancer Res. Treatment 19: 123 (1991)

–      Abraha E., Fuller L., Vivier A., et al.: Serum S-100 protein? A potencially useful prognostic marker in coutaneous melanoma. Br J. Dermatol. 137: 381-385(1997)

–      Al-Awadhi A., Ohisi S., Al-Zaid N., et al.: Serum concentrations of interleukin 6, osteocalcin, intact par hormone, and markers of bone resorption in patients with rheumat arthritis. J Rheumatol. 26: 1250-1256 (1999)

–      Ballesta A., Molina R., Filella X., et al.: Carcinoembryonic antigen in staging and follow-up of patients with solid tumors. Tumor Biol. 16: 32-41 (1995)

–      Buer X., Probst M., Franzke A., et al.: Elevated serum levels of S-100 and survival in metastatic malignant melanoma. Br J. Cancer 75: 1373 -1376 (1997)

–      Buzald A., Tinoco L., Jenendiroba D., et al.: Prognostic value of size of lymph node metastases in patients with cutaneous melanoma. J. Clin. Oncol. 13: 2361-2368 (1995)

–      Catalona W., Partin A., Stawin K., et al.: Use of the percentage of free prostate-specific antigen to enhance differentiation of prostate cancer from benign prostatic disease? A prospective multicenter clinical trial. JAMA 279: 1542-1547 (1998)

–       Chaniotis D., Karageorgos G., Petropoulos P., Chaniotis F.: Effect of digestive and pulmonary system infections on renal function. Rev. Clin. Pharmacol. Pharmacokinet.Int.. Ed. 20: 43-48 (2006)

–       Chaniotis F.I., Chaniotis D.I.: Cardiac cachexia. Hellenic J. Cardiol. 38: 94-98 (1997)

–      Crawford E., Schutz M., Clejan S., et al.: The effect of digital rectal examination on prostate-specific antigen levels. JAMA 267: 2227-2228 (1992)

–      DeVita V., Hellman S., Rosenberg S.: CANCER, Principles and Practice of Oncology. Lippincott, Williams and Wilkins, 2001

–      Elledge G., McGulre W.: Prognostic factors and therapeutic decisions in axillary node-negative breast. Rev. Med. 44: 201-210 (1993)

–      Fletcher R.: Carcinoembryonic antigen. Ann. intern. Med. 104: 63-73 (1996)

–      Gion M, Mone R., Leon A., et al.: Comparison of the diagnostic accuracy of CA 27.29 and CA 15-3 in primary breast cancer. Clin. Chem. 45: 630-637 (1999)

–      Hayes D., Zurafski V., et al.: Comparison of circulating CA 15-3 and carcinoembryonic antigen levels in patients with breast cancer. J. din. Oncol. 4 1542-1550 (1986)

–      Henze G., Dummer R., Joller-Jemeika H., et al.: Serum S-100: a marker for disease monitoring in metastatic melanoma. Dermatology 194: 208-212 (1997)

–      Huhtala M., Kahampas K., Seppala M., et al.: Excretion of a tumor-associated TAH in urine of patients with gynecological malignancy. Inter. J Cancer 31: 711-714 (1983)

–      Isola J., Visacorp T., Holli K., et al.: Association of p53 expression with other prognostic factors survival in node-negative breast cancer. J Cell. Biochem. (Suppl. 16D): 101 (1992)

–      Jarvisalo X., Hakama M., Knekt P., et al.: Serum tumor markers CEA, CA 50, TA1T and NSE in lung cancer screening. Cancer 71: 1982 -1988 (1993)

–      Johnson P.: The role of serum alpha-fetoprotein estimation in the diagnosis and management of hepatocellular carcinoma. Cm. Liver Dis. 5: 145-159 (2000)

–      Kamell R., von Schoultz E., Hansson L., et al.: S-100 protein, 5-S-cysteinyldopa and hydroxy6-5-methoxyindole-2-carboxylic acid as biochemical markers for survival prognosis in patients with malignant melanoma. Melanoma Res. 7: 393-399 (1997)

–      Koeler G., Milstein C.: Continuous culture of fused cells secreting antibody of predefined specificity. Nature 256: 495-496 (1975)

–      Lasson A., Borgstrorn A., Ohlsson K.: Elevated pancreatic secretory trypsin inhibiter levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures. Scand. J Gastroenterol. 21: 1275-1280 (1986)

–      Lotnicker M., Pavesi F., Scarabelli M.: Tumor associated antigens CA 15-3 and CA 12-5 in ovarian cancer. Markers 6: 115 (1991)

–      Malkasian G., Knapp R., Lavin P., et al.: Preoperative evaluation of serum CA 12-5 levels in postmenopausal and postmenopausal patients with pelvic masses’ discrimination of benign from malignant disease. Am. J. Obstet. Gynecol. 159: 341-346 (1988)

–      Massaron S., Seregni E., Luksch R., et al.: Neuron-specific enolase evaluation in patients with neuroblastoma. Tumor Biology 19: 261-268 (1998)

–      McGulre W., Tandon A., Alfred D., et al.: How to use prognostic factors in axillary breast cancer patients. J Nat Cancer Inst. 82: 1006 -1007 (1990)

–      Michael H., Torosian M.: The clinical usefulness and limitations of tumor markers. Surg. Gynecol. Obstet. 166: 567-579 (1988)

–      Missotten G., Tang N., Korse C., et al.: Prognostic value of S-100 (beta) serum concentration in patients with uveal melanoma. Arch. Ophthalmol. 121: 1117-1119 (2003)

–      Oesterling X., Martin S., Bergstralh, et al.: The use of prostatic specific antigen in staging patients with newly diagnosed prostate cancer. JAMA 269: 57-60 (1993)

–      Partin A., Carter H., Chan D., et al.: Prostate specific antigen in the staging of localized prostate cancer? Influence of tumor differentiation, tumor volume and benign hyperplasia. J Urol. 143: 747-752 (1990)

–      Partin A., Yoo J, Carter H., et al.: The use of PSA clinical stage in men with localized prostate cancer. J. Urol. 150: 110-114 (1993)

–      Pasanen P., Eskelinen M., Partanen E.L., et al.: Multivariate analysis of six serum tumor markers (CEA, CA 50, CA 242, TPA, TPS, TATI) and conventional laboratory tests in the diagnosis of hepatopancreatobiliary malignancy. Anticancer Res. 15: 2731-2737 (1995)

–      Pectasides D., Bafaloucos D., Antoniou F., et al.: TPA, TATI, CEA, AFP, b-HCG, PSA, SCC and CA 19-9 for monitoring transitional cell carcinoma of the bladder. Am. J Cm. Oncol. 19: 271-277 (1996)

–      Peters-Engl C., Buxbaum P., Ogris E., et al.’ TATI and cancer antigen CA 12-5 in patients with early-stage endometrial cancer. Anticancer Res. 18: 4635-4639 (1998)

–      Piantino P., Arosaio E.: TATI in gastrointestinal cancer and related benign diseases. Scand. J Clin. Labors Invest. 51: 67-69 (1991)

–      Stanmey T., Yang N., Hay A., et al.: Prostate specific antigen as a serum marker for adenocarcinoma of the prostate. N. Engl. J Med. 317: 909-916 (1987)

–      Stenman U., Koivunen E., Itkonen O., et al.: Clinical use and biological function of TATI. Pp. 351-361, Edizione Minerva Medica S.P.A., Torino, 1993

–      Tchetgen M., Oesterling J.: The effect of prostatitis, urinary refentio in, ejaculation and ambulation of the serum prostate-specific antigen concentration. Urol. Clin. North Am. 24: 283-291 (1997)

–      Tramonti G., Ferdeghini M., Donatio C., et al.: Serum level of five tumor markers (TATI, SCC, Cyfia 21-1, TPA, TPS) and renal function. Intern. Symposium of the Impact of Biotechnology on Prediction, Prevention and Treatment of Cancer, Nice France, Oct. 24-27, 1998

–      Tripatzis L.: Monoclonical antibodies. Medical Sep. No 4 68-72 (1989)

–      Wibe E., Hannisdal E., Paus E., et al.: Neuron-specific enolase as a prognostic factor in metastatic malignant melanoma. Eur J. Cancer 28A: 1692-1695 (1992)

–      For moreover data regarding the classification of cancer markers, it can find no one in the web pages’

http://www.asco.org (Am. Soc. of Clin. One. – ASCO) //www.ahsmedicare.com/medical review appeals (Associated Hospital Service-AHS) l/libraryumsmededu/medi-immutum //www.empiremedicare.com/

while for abundance of information in the web pages of international organisms of health, pharmaceutical houses, etc.

Relative Papers

Online ISSN 1011-6575

Άρθρα Δημοσιευμένα σε αυτό το Περιοδικό Καταχωρούνται στα:

Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor

Τι είναι η Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση-Οδηγίες προς τους Συγγραφείς – 
What is Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition-Instrunctions to Authors

Άρθρα Δημοσιευμένα στην Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – 
Articles Published in Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Συντακτικη Επιτροπή-Editorial Board

ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 2007 – ANNUAL SUBSCRIPTION 2007
Γλώσσα Πλήρους Κειμένου – Full Text Language Αγγλικά – English
Παραγγελία – Αγορά – Order – Buy Ηλεκτρονική Μορφή: pdf (70 €) – Digital Type: pdf (70 €)

pharmakonpress[at]pharmakonpress[.]gr

Έντυπη Μορφή (70 € + έξοδα αποστολής) – Printed Type (70 € + shipping)

pharmakonpress[at]pharmakonpress[.]gr

 

 

 

Bookmark the permalink.

Comments are closed.