| Title | The implication of beta-amyloid peptides in Alzheimer’s disease | |
| Authors | Vasiliki-Sofia Grech1, Antonios Togias2, Maria Grech3 and Ioanna Grech4
1. Biochemistry Department, Medical Biochemistry, School of Biomedical and Health Science, King’s College London, London, UK 2. Physician, Athens, Hellas 3. Physician, Scientific Collaborator, Hippokrateion Hospital, Athens, Hellas 4. Department of Aestheticsand Cosmetology, School for Professions of Health and Welfare, Technological Educational Institution of Athens, Egaleo, Athens, Hellas |
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| Citation | Grech, V.-S., Togias, A., Grech, M., Grech, I.: The implication of beta-amyloid peptides in Alzheimer’s disease, Epitheorese Klin. Farmakol. Farmakokinet. 23(3): 131-137 (2009) | |
| Publication Date | Accepted for publication (Final Version): July 1, 2009 | |
| Full Text Language | English | |
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| Keywords | β-Amyloid, Aβ(25-35), Aβ(1-40), Alzheimer’s disease (AD). | |
| Other Terms | review article | |
| Summary | There are a number of publications supporting that progressive neurodegeneration of Alzheimer’s disease (AD) is to a certain extent based on β-amyloid protein. A connection between β-amyloid aggregation and its ability to endorse in vitro degeneration is a rather promising area for deep scientific research. One of these scientific queries is plotted in the A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease article, written by Hensley et al. in 1994. This article is going to focus on the background of Hensley’s publication and evaluate the scientific field. Therefore, analysis and comparison of the materials and methods used and personal estimations are determined in order to fulfill this critical review. | |
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Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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