Τόμος 24 (2010) – Τεύχος 1 – Άρθρο 4 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 24 (2010) – Issue 1 – Article 4 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Surveillance of health care associated infections in patients after coronary artery bypass graft surgery
Authors Kiriaki Roulia and Eleni Apostolopoulou

Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Hellas

Citation Roulia, K., Apostolopoulou, E.: Surveillance of health care associated infections in patients after coronary artery bypass graft surgery, Epitheorese Klin. Farmakol. Farmakokinet. 24(1): 25-30 (2010)
Publication Date Accepted for publication (Final Version): April 10, 2010
Full Text Language English
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Keywords Health care associated infections, coronary artery bypass grafting, complications, risk factors, surgical wound, infection control, prevention.
Other Terms review article
Summary A retrospective survey was performed to determine the incidence rate and incidence density rate, and to identify the risk factors associated with Healthcare Associated Infections (HAIs) after coronary artery bypass graft (CABG) within 30 days. The study occurred during a two-month period in a cardiac surgery center in Athens, Greece, that is a referral center for patients with cardiovascular diseases. All patients undergoing CABG surgery were selected for this investigation. A standardized Surveillance system based on the National Nosocomial Infections Surveillance (NNIS) of the Centers for Disease Control and Prevention (CDC) was implemented. The study included 136 patients (1331 patient-days). Among the 136 patients, 36 (26.5%) had in total 50 HAIs (36.8%). Among the 36 patients with HAIs, 28 (77.8) had a single infection, 8 (22.2%) had two infections. The majority of SSIs (90.5) on the leg and sternal site was diagnosed after discharge from hospital. The incidence rate of HAIs was 36.8% and the incidence density of HAIs was 37.6 infections per 1000 patient-days. The incidence rate of SSI at the leg was 12.5%, blood stream infection 8.1%, respiratory tract infection and urinary tract infection 6.6% and sternal site infection 2.9%. The incidence density of SSI at the leg was 12.8 infections per 1000 patient-days, blood stream infection 8.7 per 1000 patient-days, respiratory tract infection and urinary tract infection 6.8 infections per 1000 patient-days, and sternal site infection 3 infections per 1000 patient-days. A multivariate model showed that only two risk factors were significantly and independently responsible for HAIs after CABG surgery: Diabetes (AOR 1.781, 95% CI 1.240-2.551, P=0.002), and Peripheral vascular disease (AOR 1.642, 95% CI 1.161-2.332, P=0.005). These results show that the factors that had most influence on the development of HAIs after CABG surgery were patient related factors.
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