Τόμος 27 (2013) – Τεύχος 1 – Άρθρο 3 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 27 (2013) – Issue 1 – Article 3 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Blood lipids in patients suffering from colorectal cancer
Authors Erasmia Singelaki, Nikolaos Nikiteas and Andreas Manouras

First Department of Propaedeutic Surgery, Hippokrateion Hospital, Athens Medical School, University of Athens, Hellas

Citation Singelaki, E., Nikiteas, N., Manouras, A.: Blood lipids in patients suffering from colorectal cancer, Epitheorese Klin. Farmakol. Farmakokinet. 27(1): 33-38 (2013)
Publication Date Accepted for publication (Final Version): April 10, 2013
Full Text Language English
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Keywords Colorectal cancer, blood lipids, patients.
Other Terms review article
Summary INTRODUCTION: The cause of cancer of the large intestine is unknown. Predispositional factors have been implicated related to concurrent large intestine diseases such as polyposis, ulcerous colitis, Crohn’s disease and infection of Epstein Bar Virus, while in the past fifteen-year period there has been discussion on the relation between lipids and the presence of colorectal cancer. MATERIAL: The study of this issue took into consideration the lipoprotein electrophoresis data of 162 colorectal cancer patients and 67 healthy subjects. The cancer patients comprised of 88 males and 74 females while the healthy subjects were 37 men and 30 women. RESULTS: The average HDL value of the patients was higher (51.00 mg/dl) as opposed to that of the healthy subjects (28.13 mg/dl). The average beta value of the patients was 47.1% compared to 53.32% of the healthy subjects. The average pre-beta value was greater (23.63%) than the respective value for healthy subjects (17.95%). The average Lp(a) of the patients was 33.67% compared to 0.84% of the healthy subjection. CONCLUSION: Therefore lipoprotein electrophoresis is an examination that may be used for the control of patients suspected of cancer in the large intestine.
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